Mangaladevi Menon

article 1986

Inhibition of gonadotropin-releasing hormone receptors in rat anterior pituitary monolayer cell cultures by danazol

·doi:10.1016/0002-9378(86)90673-3

To study possible cellular antigonadotropic effects of danazol, monolayer cultures of anterior pituitary cells from immature female rats were treated with danazol. Measurements of luteinizing hormone release in response to 10(-8) mol/L gona…

article 1981

In Vitro Effect of Danazol on Luteinizing Hormone-Releasing Hormone-Stimulated Luteinizing Hormone Release in Rat Anterior Pituitary Cell Cultures in Vitro *

Endocrinology ·doi:10.1210/endo-109-1-191

Monolayer cultures of anterior pituitary glands from female rats were exposed to 5 X 10(-6) M danazol for 0, 4, 24, 48, and 72 h in Dulbecco's Modified Eagle's Medium supplemented with 10% horse serum and 2.5% fetal calf serum. After this t…

article 1980

Evidence that danazol inhibits gonadotropin-induced ovarian steroidogenesis at a point distal to gonadotropin-receptor interaction and adenosine 3′,5′ cyclic monophosphate formation

·doi:10.1016/0002-9378(80)90683-3

The action of danazol on 125I-human chorionic gonadotropin (hCG) binding, gonadotropin-stimulated adenosine 3',5' cyclic monophosphate (cAMP) accumulation and progesterone production has been investigated in luteinized rat ovaries. Preincub…