Heather C Whalley

No ORCID on file · 5 papers in corpus · active 2019-2025

Study types

  • other 2
  • article 1

Condition tags

  • chronic_pelvic_pain 2
other 2025
Statistical learning to identify and characterise neurodevelopmental outcomes at 2 years in babies born preterm: model development and validation using population-level data from England and Wales
EBioMedicine ·doi:10.1016/j.ebiom.2025.105811

BACKGROUND: Children born preterm face elevated risks of neurodevelopmental impairments across domains. Prior studies have relied on expert-imposed typologies within single domains. This study applies statistical learning to a national data…

other 2024
Genome-wide association reveals a locus in neuregulin 3 associated with gabapentin efficacy in women with chronic pelvic pain
iScience ·doi:10.1016/j.isci.2024.110370

Chronic pelvic pain (CPP) in women with no obvious pelvic pathology has few evidence-based treatment options. Our recent multicenter randomized controlled trial (GaPP2) in women with CPP and no obvious pelvic pathology showed that gabapenti…

2023
Epigenetic scores indicate differences in the proteome of preterm infants
·doi:10.1101/2023.12.19.23300227

Background Epigenetic scores (EpiScores), reflecting DNA methylation (DNAm)-based surrogates for complex traits, have been developed for multiple circulating proteins. EpiScores for pro-inflammatory proteins, such as C-reactive protein (DNA…

2019
Epigenetic prediction of major depressive disorder
·doi:10.1101/19001123

Objective DNA methylation (DNAm) is associated with environmental risk factors for major depressive disorder (MDD) but has not yet been tested for its ability to discriminate individuals with MDD from unaffected individuals. Methods Using p…

article 2019
The use of brain functional magnetic resonance imaging to determine the mechanism of action of gabapentin in managing chronic pelvic pain in women: a pilot study
BMJ open ·doi:10.1136/bmjopen-2018-026152

OBJECTIVE: To inform feasibility and design of a future randomised controlled trial (RCT) using brain functional MRI (fMRI) to determine the mechanism of action of gabapentin in managing chronic pelvic pain (CPP) in women. DESIGN: Mechanist…