Joanne B. Weidhaas

ORCID: 0000-0002-5096-3281 · 4 papers in corpus
article 2019
Lack of an Association between a Polymorphism in the KRAS 3′ Untranslated Region (rs61764370) and Endometriosis in a Large European Case-Control Study
Gynecologic and obstetric investigation ·doi:10.1159/000500626

BACKGROUND: Endometriosis is a common disorder that affects 6-10% of reproductive age women. In a previous study, we demonstrated that a polymorphism in let-7 microRNA-binding site in the 3' untranslated region of the KRAS gene was found in…

article 2012
A polymorphism in a let‐7 microRNA binding site of KRAS in women with endometriosis
EMBO molecular medicine ·doi:10.1002/emmm.201100200

Endometriosis is found in 5-15% of women of reproductive age and is more frequent in relatives of women with the disease. Activation of KRAS results in de novo endometriosis in mice, however, activating KRAS mutations have not been identifi…

2010
A KRAS-variant in ovarian cancer acts as a genetic marker of cancer risk.
Cancer research ·doi:10.1158/0008-5472.can-10-0689

Ovarian cancer (OC) is the single most deadly form of women's cancer, typically presenting as an advanced disease at diagnosis in part due to a lack of known risk factors or genetic markers of risk. The KRAS oncogene and altered levels of t…

2010
MicroRNA signatures differentiate uterine cancer tumor subtypes.
Gynecologic Oncology ·doi:10.1016/j.ygyno.2010.05.010

ObjectiveEndometrial cancer (EC) is the most common gynecologic malignancy. Type I EC has a favorable prognosis, while type II ECs account for half of all treatment failures. Little knowledge of the biological differences is available to pr…