G. Canny

ORCID: 0000-0003-0632-7365 · 14 papers in corpus
preprint 2024
·doi:10.1101/2024.05.06.24306766

Abstract Progress in detecting and understanding endometrial conditions in women of fertile age, such as endometriosis, has been hampered by the invasiveness of the sample collection procedure. Menstrual fluid (MF) can be sampled non-invasi…

preprint 2024
·doi:10.7554/elife.99558

Abstract Progress in detecting and understanding endometrial conditions in women of fertile age, such as endometriosis, has been hampered by the invasiveness of the sample collection procedure. Menstrual fluid (MF) can be sampled non-invasi…

preprint 2024
·doi:10.7554/elife.99558.1

Abstract Progress in detecting and understanding endometrial conditions in women of fertile age, such as endometriosis, has been hampered by the invasiveness of the sample collection procedure. Menstrual fluid (MF) can be sampled non-invasi…

article 2018
European review for medical and pharmacological sciences ·doi:10.26355/eurrev_201812_16549

OBJECTIVE: Endometriosis is a debilitating disease characterized by chronic inflammation. The transporter multidrug resistance-associated protein 4 (MRP4/ABCC4) is expressed in human endometrial tissue; it is overexpressed in ectopic endome…

other 2017
Reproductive sciences (Thousand Oaks, Calif.) ·doi:10.1177/1933719116649695

The objective of the present study was to test the ability of OSU-03012 (2-amino-N-[4-[5-phenanthren-2-yl-3-(trifluoromethyl)pyrazol-1-yl]phenyl]acetamide), a novel and potent celecoxib-derivative, to impair endometriosis progression in in …

article 2016
Frontiers in endocrinology ·doi:10.3389/fendo.2015.00192

Endometriosis affects approximately 10% of women of reproductive age. This chronic, gynecological inflammatory disease results in a decreased quality of life for patients, with the main symptoms including chronic pelvic pain and infertility…

book-chapter 2014
·doi:10.1007/978-4-431-54421-0_17
other 2014
PloS one ·doi:10.1371/journal.pone.0089742

Endometriosis, a leading cause of pelvic pain and infertility, is characterized by ectopic growth of endometrial-like tissue and affects approximately 176 million women worldwide. The pathophysiology involves inflammatory and angiogenic med…

other 2013
Fertility and sterility ·doi:10.1016/j.fertnstert.2013.01.146

OBJECTIVE: To compare the expression of the prostaglandin (PG) E(2) transporter multidrug resistance-associated protein 4 (MRP4) in eutopic and ectopic endometrial tissue from endometriosis patients with that of control subjects and to exam…

article 2013
PloS one ·doi:10.1371/journal.pone.0082512

BACKGROUND/AIMS: The neural cell adhesion molecule L1CAM is a transmembrane glycoprotein abnormally expressed in tumors and previously associated with cell proliferation, adhesion and invasion, as well as neurite outgrowth in endometriosis.…

article 2013
·doi:10.1016/j.fertnstert.2013.07.1578
review 2013
Mucosal immunology ·doi:10.1038/mi.2013.9

Lipoxin A4 (LXA4), an endogenous anti-inflammatory and immunomodulatory mediator studied in many disease states, is recently appreciated as a potentially significant player in the endometrium. This eicosanoid, synthesized from arachidonic a…

article 2012
Fertility and sterility ·doi:10.1016/j.fertnstert.2012.06.056

ObjectiveTo analyze the expression of estrogen receptors α and β as well as their target genes implicated in proliferation, c-myc, cyclin D1, and GREB1, in the endometrium of women with or without endometriosis.DesignExpression analysis in …

other 2011
Molecular and cellular endocrinology ·doi:10.1016/j.mce.2011.06.043

The pro-inflammatory cytokine TNF-α and the female hormone estrogen have been implicated in the pathophysiology of two common gynecological diseases, endometriosis and endometrial adenocarcinoma. Here we describe a novel capacity of TNF-α t…