Liu M

BACKGROUND: Endometriosis (EM) is a chronic, estrogen-dependent disease that lacks reliable noninvasive diagnostic biomarkers. This study was aimed at evaluating the diagnostic value of PAX8 using integrated transcriptomic and machine learn…

BACKGROUND: This study aimed to establish the diagnostic cut-off value of serum Anti-Müllerian Hormone (AMH) for Polycystic Ovary Syndrome (PCOS) in Chinese women of reproductive age and explore its diagnostic efficacy, particularly in rela…

OBJECTIVE: There is currently no consensus on the risk factors for recurrent ovarian endometrioma after surgery. This study aimed to identify independent risk factors and develop a clinical nomogram to predict postoperative recurrence. MET…

Background/Objectives: Primary dysmenorrhea is a common gynecological disorder characterized by painful uterine contractions. Danggui Buxue Decoction (DBD) is used to treat menstrual irregularities, but its mechanism in primary dysmenorrhea…

BackgroundPostmenopausal women are at elevated risk for carotid atherosclerosis due to estrogen decline, yet existing prediction models do not incorporate genetic markers. This study aimed to develop and validate a risk prediction model com…

BackgroundEndometrial receptivity (ER) is critical for embryo implantation, and its impairment is a major contributor to infertility. Current ER evaluation methods are invasive and poorly standardized. Shear wave elastography (SWE) offers a…

Earlier examinations of how risk factors relate to endometriosis (EMT) have largely depended on observational designs, which arrived at conflicting conclusions. The present approach seeks to probe the causal association between 108 traits a…

Ovarian cancer was the eighth most frequently diagnosed cancer among women in 2022. The global age-standardized incidence rate of ovarian cancer decreased from 7.22/100,000 to 6.71/100,000 from 1990 to 2021. However, incidence trends varied…

Acute pancreatitis (AP) is a frequent inflammatory disorder with outcomes ranging from mild disease to severe forms marked by infection and organ failure. Gut microenvironment disruption and barrier dysfunction are increasingly recognized a…

Endometriosis (EMs) is a chronic gynecological disease with poorly understood pathogenesis. This study integrated lipidomics and transcriptomics to systematically investigate aberrant sphingolipid metabolism in EMs, aiming to identify patho…

The clinical management of endometriosis encounters a significant obstacle: existing therapies inadequately address both the inhibition of ectopic lesion proliferation and the mitigation of the neuroinflammation associated with chronic pain…

High-throughput omics technologies have transformed our understanding of female reproductive biology, revealing molecular interactions governing oocyte maturation, ovarian reserve, endometrial receptivity, and embryo development, yet most f…

Dairy cow endometritis is a common postpartum disease influenced by geographic, management, environmental, diagnostic, and socio-economic factors. Escherichia coli (E. coli) was prioritized for its early colonization, frequent detection, an…

The central nervous system regulates glandular secretions by modulating visceral organ functions. However, the anatomical and functional connections between the brain and digestive enzyme-producing pancreatic acinar cells remain poorly defi…

Objective: To develop and compare a random survival forest (RSF) model and a Cox regression model-for predicting postoperative recurrence in patients with ovarian endometrioma. Methods: The primary outcomes of the study were the recurrence …

Endometriosis, a chronic inflammatory condition characterized by pain and infertility, remains a clinical challenge. Current hormonal and surgical treatments are often limited by side effects and high recurrence rates. In search of more eff…

ObjectivesEndometrial receptivity lacks robust biomarkers. Given its role in stabilizing the progesterone receptor, the epigenetic regulator BMI1 is a key candidate, yet its clinical potential is undefined. This study aimed to characterize …

Ectopic spleen (ES) is a rare complication of autologous transplant following spleen injury. Autopsy studies suggest that the true incidence rate could be as high as 67%, though only 5%-10% of patients require clinical intervention. This ca…

BackgroundPolycystic ovary syndrome (PCOS) is widely acknowledged as the prevailing reproductive endocrine disorder accompanied by numerous metabolic dysfunctions. However, there has been a lack of systematic examination regarding the amino…

Angiogenesis is critical from early development through the progression of life-threatening diseases. In rheumatoid arthritis (RA), angiogenesis is markedly heightened and undergoes aberrant changes that exacerbate the progression of synovi…

The high rate of unexplained female infertility significantly affects public health and women's mental well-being. Research on dietary nutrients' impact on infertility often overlooks vitamin B2. Exploring this vitamin's role could be cruci…

BACKGROUND: Uterine fibroids and endometriosis are common benign gynecological diseases affecting the health of women of childbearing age, characterized by high incidence and recurrence rates. Despite the increasing global emphasis on women…

BackgroundAlthough azithromycin has demonstrated potential therapeutic efficacy in the treatment of chronic endometritis (CE), comprehensive studies on the optimal timing of administration are lacking. Our study aims to evaluate the impact …

BACKGROUND: Fibrogenesis is a common pathological feature of endometriotic lesions and contributes to the development of endometriosis-associated chronic pelvic pain and infertility. TGF-β is a critical factor in the induction of fibrogenes…

Intracerebral hemorrhage (ICH) is a most serious type of hemorrhagic stroke with a continuously rising incidence globally, without effective cure available. The underlying mechanisms driving brain injury are complex and include inflammation…