To evaluate the association between implementation of a standardized endocavitary sonography image-documentation protocol, developed in accordance with the International Deep Endometriosis Analysis (IDEA) consensus, and the diagnostic perfo…
Endometriosis is a common, estrogen-driven chronic gynecologic disorder defined by the ectopic growth of endometrial-like tissue within the peritoneal cavity. Existing treatment options, primarily surgery and hormonal therapy, are limited b…
OBJECTIVE: To compare the clinical efficacy of letrozole-induced ovulation cycles, natural cycles, and Hormonal Replacement Therapy cycle in frozen embryo transfer (FET), and to investigate the effects of different endometrial preparation p…
BACKGROUND: Endometriosis (EMs) is a common gynecological disorder characterized by ectopic endometrial tissue growth, leading to chronic inflammation and pelvic pain. Despite its high prevalence, the molecular mechanisms underlying EMs rem…
Organoids are three-dimensional multicellular structures derived from stem cells or primary tissues that recapitulate key structural and functional features of native organs. Advances in stem cell biology, biomaterials, and bioengineering h…
BACKGROUND: With the rising rate of cesarean section delivery worldwide, the development of cesarean scar diverticulum (CSD) is increasingly observed, with a prevenance ranging from 24% to 70%. CSD is associated with abnormal uterine bleedi…
INTRODUCTION: Chronic endometritis (CE) is regarded as a potential factor contributing to infertility and embryo implantation failure. The cause of CE remains unclear at present, but it might be associated with intrauterine microbial infect…
PURPOSE: To explore the impact of seasonal variations on the risks of hypertensive disorders of pregnancy (HDP) and gestational diabetes mellitus (GDM) in women who undergo in vitro fertilization (IVF) treatment. METHODS: We retrospectivel…
BACKGROUND: While anti-Müllerian hormone (AMH) serves as a well-established biomarker of ovarian reserve, its association with early miscarriage risk remains inconsistently characterized across previous research. To address this evidence ga…
Deep infiltrating endometriosis (DIE) is a severe condition frequently linked to infertility, yet the optimal integration of surgery and assisted reproductive technology (ART) remains controversial. This study reports two cases of infertili…
RESEARCH QUESTION: Does frozen embryo transfer improve pregnancy outcomes compared with fresh embryo transfer in women with ovarian endometriosis (OEM) undergoing their first IVF/intracytoplasmic sperm injection cycle? DESIGN: A retrospect…
PURPOSE: Maternal age-related fertility decline is considered to be directly attributed to either embryonic or endometrial factors. Aneuploidy, as the dominant defect in aging embryos, has long diverted attention away from the effects of en…
Extracellular vesicles (EVs) have emerged as pivotal mediators of intercellular communication in reproductive medicine, demonstrating considerable potential for both understanding and treating reproductive disorders. By precisely regulating…
The increased risk of infertility and endometrial lesions (such as endometrial hyperplasia or cancer) in polycystic ovary syndrome (PCOS) are closely associated with the lack of cyclical transformation in the endometrium. However, the under…
BACKGROUND: Endometriosis is an estrogen-dependent, progesterone-resistant gynecological disorder, with dysmenorrhea being the most common manifestation. OBJECTIVE: This study evaluates the efficacy and safety of the Tibetan herbal medicat…
BACKGROUND: Environmental endocrine disruptor Di (2-ethylhexyl) phthalate (DEHP) widely affects the health of human and animals including the reproductive system. However, there are few studies on the protective strategies for the maternal …
OBJECTIVE: To analyze the ultrasonographic imaging features of accessory cavitated uterine malformations (ACUM) and discuss the practical value of ultrasonography in diagnosing this disease. METHODS: A retrospective analysis was conducted …
BACKGROUND: Endometrial hyperplasia (EH) is a precursor to endometrial cancer, and the role of the microbiome in its development is unclear. RESULTS: The present study investigated the uterine microbiome in patients with benign uterine con…
To evaluate the repeatability of a novel automated technique called Smart ERA (Smart Endometrial Receptivity Analysis) for the automated segmentation and volume calculation of the endometrium in patients with normal uteri,, and to compare t…
INTRODUCTION: The potential role of the endometrial microbiota in the pathogenesis of endometrial polyps (EPs) warrants further investigation, given the current landscape of limited and inconclusive research findings. We aimed to explore th…
Mucinous ovarian carcinoma (MOC) represents a distinct entity within ovarian malignancies, characterized by diagnostic challenges due to its rarity and the potential overlap with other tumor types. The determination of tumor origin is impor…
BACKGROUND: To systematically assess and compare the predictive value of the Ranson and Bedside Index of Severity in Acute Pancreatitis (BISAP) scoring systems for the severity and prognosis of acute pancreatitis (AP). METHODS: PubMed, Emb…
There is limited research on risk factors for chronic endometritis regarding reproductive history and clinical symptoms. Thus, this nested case-control study identified risk factors for chronic endometritis in women who have undergone hyste…
BACKGROUND: This study investigates the differences in the cost, time, pre-operative education and patient satisfaction levels of patients requiring a second hysteroscopic surgery using a full-service model of remote preoperative assessment…