MacLean JA 2nd

No ORCID on file · 3 papers in corpus · active 2016-2024

Study types

  • article 2
  • other 1

Condition tags

  • endometriosis 3
  • chronic_pelvic_pain 1
  • infertility 1
article 2024
High-fat diets promote peritoneal inflammation and augment endometriosis-associated abdominal hyperalgesia
Frontiers in endocrinology ·doi:10.3389/fendo.2024.1336496

Immune dysfunction is one of the central components in the development and progression of endometriosis by establishing a chronic inflammatory environment. Western-style high-fat diets (HFD) have been linked to greater systemic inflammation…

other 2024
The involvement of peritoneal GATA6+ macrophages in the pathogenesis of endometriosis
Frontiers in immunology ·doi:10.3389/fimmu.2024.1396000

Endometriosis is a chronic inflammatory disease that causes debilitating pelvic pain in women. Macrophages are considered to be key players in promoting disease progression, as abundant macrophages are present in ectopic lesions and elevate…

article 2016
Niclosamide As a Potential Nonsteroidal Therapy for Endometriosis That Preserves Reproductive Function in an Experimental Mouse Model
Biology of reproduction ·doi:10.1095/biolreprod.116.140236

Endometriosis causes severe chronic pelvic pain and infertility. Because the standard medication and surgical treatments of endometriosis show high recurrence of symptoms, it is necessary to improve current treatment options. In the initial…