Massimo Candiani

ORCID: 0000-0002-2129-2626 · 179 papers in corpus
nonrandomized-trial 2005
Journal of Minimally Invasive Gynecology ·doi:10.1016/j.jmig.2005.06.006

STUDY OBJECTIVE: To evaluate damage to ovarian reserve following laparoscopic cystectomy of benign ovarian cysts. DESIGN: Prospective study (Canadian Task Force classification II-3). SETTING: Tertiary gynecologic endoscopic unit at a univ…

observational 2005
Journal of Minimally Invasive Gynecology ·doi:10.1016/j.jmig.2005.06.016

STUDY OBJECTIVE: To evaluate the risk of recurrence of deep endometriosis after conservative surgery. DESIGN: Retrospective analysis (Canadian Task Force classification II-3). SETTING: Tertiary care university hospital. PATIENTS: One hun…

observational 2005
Molecular human reproduction ·doi:10.1093/molehr/gah225

An autoimmune etiology has been suggested for endometriosis mostly on the basis of an increased prevalence of autoimmune diseases in affected women. Cytotoxic T lymphocyte antigen (CTLA) 4 gene is recognized as a primary determinant for aut…

observational 2004
Molecular human reproduction ·doi:10.1093/molehr/gah093

Endometriosis is a benign gynaecologic disease that is associated with a certain risk for malignant degeneration. The disease has a genetic background, but the locations of possible genomic aberrations are still poorly clarified. In this co…

observational 2004
Clinical endocrinology ·doi:10.1111/j.1365-2265.2004.02076.x

OBJECTIVE: Endometriosis is a steroid-dependent disease with a particular genetic background, but the locations of possible genomic aberrations are still poorly clarified. We have investigated the potential association between endometriosis…

observational 2003
Human Reproduction ·doi:10.1093/humrep/deg513

BACKGROUND: It has been suggested recently that deep endometriosis and the other forms of the disease do not share a common pathogenetic mechanism. In this study, we hypothesize that, if this is true, deep peritoneal endometriosis and the o…

rct 2002
·doi:10.1097/00006254-200205000-00018

Symptomatic women with stage III to IV endometriosis today are most often managed by conservative laparoscopic surgery, but recurrences continue to occur. Roughly one in five patients will have further disease within 5 years after complete …

case-report 2002
·doi:10.1089/104240602760363655

Gynecologic and obstetric pathologies may be associated with the presence of a cavitate rudimentary horn such as hematometra, chronic pelvic pain, severe dysmenorhea, increased risk of endometriosis, uterine rupture in pregnancy when implan…

other 2002
Fertility and sterility ·doi:10.1016/s0015-0282(02)02971-0

OBJECTIVE: To investigate the hypothesis that soluble intercellular adhesions molecule-1 (sICAM-1) may be used as a new serum marker of endometriosis. DESIGN: Prospective cohort study. SETTING: An academic department specializing in gynec…

lab-animal 2001
Human Reproduction ·doi:10.1093/humrep/16.6.1076

Follicular fluid from women with endometriosis has been shown to induce a higher endometrial cell proliferation than that derived from women without the disease. To elucidate this issue further, the aims of the present study were to compare…

other 2001
Fertility and sterility ·doi:10.1016/s0015-0282(01)01884-2
lab-animal 2001
Acta obstetricia et gynecologica Scandinavica ·doi:10.1034/j.1600-0412.2001.080003200.x

BACKGROUND: It is still unclear whether the immunologic perturbation observed in women with endometriosis represents an intrinsic defect of the immune system or it is consequent to the presence of endometrium in ectopic sites. The present s…

2001
·doi:10.1080/j.1600-0412.2001.080003200.x
rct 2001
Human Reproduction ·doi:10.1093/humrep/16.11.2399

BACKGROUND: In order to decrease endometriosis recurrence after surgical therapy, it has been proposed to use a post-surgical oestrogen-lowering medical treatment. Results from previous trials on this topic are contradictory. METHODS: A to…

lab-animal 2001
American journal of reproductive immunology (New York, N.Y. : 1989) ·doi:10.1034/j.1600-0897.2001.d01-22.x

PROBLEM: It has been suggested that specific mechanisms commonly used by different cellular systems to evade immunologic recognition are involved in the development of endometriosis. To gain insight into this aspect, we looked at the relati…

lab-animal 2001
Fertility and sterility ·doi:10.1016/s0015-0282(00)01659-9

OBJECTIVE: To test the possibility of using transgenic knockout mice in the study of endometriosis and to investigate specific immunologic aspects of the disease. DESIGN: Experimental blinded study. SETTING: Academic research center. ANI…

rct 1999
Human Reproduction ·doi:10.1093/humrep/14.5.1335

The effect of treatment with danazol was evaluated with respect to expectant management after laparoscopic conservative surgery. All patients conservatively operated at laparoscopy for stage III-IV endometriosis from July 1994 to October 19…

nonrandomized-trial 1999
The Journal of the American Association of Gynecologic Laparoscopists ·doi:10.1016/s1074-3804(99)80041-3

STUDY OBJECTIVE: To evaluate the efficacy of conservative laparoscopic surgery in a series of patients with stage III-IV endometriosis. DESIGN: Prospective study (Canadian Task Force classification II-1). SETTING: University-affiliated ho…

nonrandomized-trial 1999
American journal of obstetrics and gynecology ·doi:10.1016/s0002-9378(99)70247-4

OBJECTIVE: Our purpose was to evaluate the recurrence rate after laparoscopic excision of ovarian endometrioma. STUDY DESIGN: An unrandomized prospective clinical study was performed at 2 tertiary-care centers of 366 patients who had a min…

other 1998
Human Reproduction ·doi:10.1093/humrep/13.8.2271

The objective of this study was to clarify which is the better surgical conservative treatment for recurrent endometriosis. We compared two consecutive surgical series at a tertiary care centre for the cure of endometriosis. The patients we…

1997
1997
·doi:10.1016/s0015-0282(97)90676-2
1996
lab-animal 1996
American journal of reproductive immunology (New York, N.Y. : 1989) ·doi:10.1111/j.1600-0897.1996.tb00179.x

PROBLEM: Development and progression of endometriosis have been suggested to be related to a defect of NK cells in the ability to eliminate endometrial fragments regurgitated with menstrual debris in ectopic sites. However, it has not been …

1996