U. Fuhrmann

No ORCID on file · 6 papers in corpus · active 2000-2014

Study types

  • article 5
  • other 1

Condition tags

  • endometriosis 6
article 2014
Human Reproduction ·doi:10.1093/humrep/deu315

Is it feasible to deliver anastrozole (ATZ), an aromatase inhibitor (AI), by a vaginal polymer-based drug delivery system in the cynomolgus monkey (Macaca fascicularis) to describe the pharmacokinetic profile? The present study showed the e…

article 2011
Gynecologic and obstetric investigation ·doi:10.1159/000331642

BACKGROUND: Dienogest demonstrates efficacy for lesion reduction and pain relief in clinical trials of endometriosis. The current study investigated an intraperitoneal animal model of endometriosis to further characterize the effects of die…

article 2008
Human Reproduction ·doi:10.1093/humrep/den189

BACKGROUND: The role of the immune system in the pathogenesis of endometriosis remains elusive. It has been shown that patients have an altered peritoneal environment with increased levels of inflammatory cytokines, activated macrophages an…

article 2007
·doi:10.1016/j.fertnstert.2007.07.207
article 2007
·doi:10.1055/s-2007-989199

Several studies have shown evidences of changes in peritoneal fluid composition in women with endometriosis. An altered function of peritoneal immune cells and higher levels of soluble substances such as cytokines, growth factors and prosta…

other 2000
Journal of medicinal chemistry ·doi:10.1021/jm001000c

Herein we describe the chemical synthesis and pharmacological characterization of a novel, highly potent progesterone receptor (PR) antagonist, ZK 230211. The introduction of a 17alpha-pentafluorethyl side chain in the D-ring of the steroid…