Zilu Zhou

ORCID: 0000-0002-5554-8490 · 3 papers in corpus
article 2026
TREM2 Deficiency Attenuates Endometriosis Progression by Inhibiting M2 Polarization of SpMs and Suppressing SIRPα to Enhance Phagocytosis
Biology of reproduction ·doi:10.1093/biolre/ioag159

Endometriosis (EMS) is characterised by a disrupted peritoneal immune microenvironment where M2 macrophage polarization and impaired phagocytosis promote lesion survival. Single-cell RNA-seq (ScRNAseq) of the peritoneal macrophages from EMS…

article 2025
Heme Inhibits the STING Pathway in Macrophages to Promote Endometriosis Development
·doi:10.1016/j.jri.2025.104695
preprint 2025
Hemin Inhibits the Activation of STING in Macrophages by Inducing HO-1, Promoting Endometriosis Development
·doi:10.1101/2025.10.25.683839

Abstract Introduction Endometriosis (EMS) is an estrogen-dependent inflammatory disorder characterized by immune dysregulation. This condition profoundly affects the quality of life and reproductive health of nearly 200 million women of rep…