Saed GM

No ORCID on file · 3 papers in corpus · active 2013-2025
2025
Anti-Mullerian hormone (AMH) protects ovarian follicle loss by downregulating granulosa cell function in in vitro and in vivo models.
Journal of assisted reproduction and genetics ·doi:10.1007/s10815-025-03473-x

PurposeAMH inhibits hormone production in luteinized granulosa cells (GCs) and stalls ovarian follicle development in vitro and in vivo. We sought to confirm AMH's mechanism of action through SMAD activation and investigate AMH inhibition o…

2014
Nicotinamide adenine dinucleotide phosphate oxidase is differentially regulated in normal myometrium versus leiomyoma.
Reproductive sciences (Thousand Oaks, Calif.) ·doi:10.1177/1933719114522552

Uterine fibroids are the most common benign tumor in women. The goal of this study was to investigate whether nicotinamide adenine dinucleotide phosphate oxidase (NOX), a major source of superoxide and subsequent oxidative stress, was diffe…

2013
Uterine fibroids are characterized by an impaired antioxidant cellular system: potential role of hypoxia in the pathophysiology of uterine fibroids.
Journal of assisted reproduction and genetics ·doi:10.1007/s10815-013-0029-7

PurposeFibroids are the most common smooth muscle overgrowth in women. This study determined the expression and the effect of hypoxia on two potent antioxidant enzymes, superoxide dismutase (SOD) and catalase (CAT) on human fibroid cells.Me…