Amal M. El-Naggar

No ORCID on file · 3 papers in corpus · active 2021-2026

Study types

  • other 1
  • preprint 1

Condition tags

  • endometriosis 1
  • endometrioma 1
  • die_deep_infiltrating 1
2026
Beyond Hydrogen Sulfide and Cysteine Metabolism: Reframing Cystathionine γ-Lyase as a Potential Translational Regulator of Hypoxia-Inducible Factor-1α in Clear Cell Ovarian Carcinoma.
Cells ·doi:10.3390/cells15121106

The canonical transsulfuration (TSS) pathway enzymes cystathionine β-synthase (CBS) and cystathionine γ-lyase (CTH) are traditionally recognized for their roles in the sequential conversion of homocysteine to cysteine and in endogenous hydr…

other 2025
Cystathionine gamma-lyase-mediated hypoxia inducible factor 1-alpha expression drives clear cell ovarian cancer progression
The Journal of Pathology ·doi:10.1002/path.6433

Clear cell ovarian cancer (CCOC) is the second most common ovarian cancer subtype, accounting for 5%-11% of ovarian cancers in North America. Late-stage CCOC is associated with a worse prognosis compared to other ovarian cancer histotypes, …

preprint 2021
A cellular and molecular portrait of endometriosis subtypes
·doi:10.1101/2021.05.20.445037

Abstract Endometriosis is a common, benign condition characterized by extensive heterogeneity in lesion appearance and patient symptoms. We profiled transcriptomes of 207,949 individual cells from endometriomata (n=7), extra-ovarian endomet…