Study types
- article 7
- review 3
- letter 1
Condition tags
- adenomyosis 11
- dysmenorrhea 3
- endometriosis 3
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Objectives: Heavy menstrual bleeding, dysmenorrhea and subfertility are associated with adenomyosis, a benign uterine condition characterised by ectopic endometrium within the myometrium. Currently, diagnosing adenomyosis is challenging. Im…
Adenomyosis, a benign yet serious uterine condition, is highly prevalent but difficult to diagnose and assess using conventional B-mode ultrasound imaging. As the formation of adenomyosis involves angiogenesis and influences local microvasc…
Heavy menstrual bleeding, dysmenorrhea and subfertility are common symptoms that are associated with adenomyosis. However, diagnosing adenomyosis remains challenging, leading to insufficient treatment options. Angiogenesis plays a pivotal r…
Abstract Study question What is the effect of anti-angiogenic therapy on adenomyosis in mice Summary answer Commencing treatment at six weeks with angiogenesis inhibitor axitinib successfully reduced the severity of adenomyosis by approxima…
The uterine junctional zone is the subendometrial area in the myometrium that contributes to peristalsis and aids in spermatozoa and blastocyst transport. Alterations in the appearance of the junctional zone on transvaginal sonography (TVS)…
BACKGROUND: Uterine disorders have clear overlapping symptoms and ultrasound discrimination is not always easy. Accurately measuring vascularity is of diagnostic and prognostic value. Power Doppler is limited to imaging only the larger vess…
There is evidence for increased angiogenesis in the (ectopic) endometrium of adenomyosis patients under the influence of vascular endothelial growth factor (VEGF). VEGF stimulates both angiogenesis and lymph-angiogenesis. However, informati…
Uterine disorders are often presented with overlapping symptoms. The microvasculature holds specific information important for diagnosing uterine disorders. Conventional sonography is an established diagnostic technique in gynecology, but i…
Contrast-enhanced ultrasound (CEUS) has the ability to visualise the microvasculature by means of intravascular contrast agents. The clinical added value of CEUS has been established in liver, kidney and cardiac imaging, but its value in gy…