Remon Roshdy Rofaeil

ORCID: 0000-0002-0159-5937 · 1 paper in corpus

lab-animal 2025

Buspirone ameliorates premature ovarian insufficiency evoked by cyclophosphamide in female rats; attention to AMPK/Nrf2/HO-1, α-Klotho/NLRP3/Caspase-1, and Caspase-3-mediated apoptosis interplay

Toxicology and applied pharmacology ·doi:10.1016/j.taap.2025.117373

This study aims to investigate the protective impact of buspirone (BUS) against cyclophosphamide (CPA)-induced premature ovarian insufficiency (POI) by focusing on pyroptosis, apoptosis, and the AMPK/Nrf2/HO-1 signaling pathway. POI was ach…