Horcajadas JA

No ORCID on file · 8 papers in corpus · active 2010-2022

Study types

  • article 5

Condition tags

  • endometriosis 4
  • infertility 2
  • adenomyosis 1
article 2022
The mid-secretory endometrial transcriptomic landscape in endometriosis: a meta-analysis
Human reproduction open ·doi:10.1093/hropen/hoac016

STUDY QUESTION: Do women with endometriosis have a different endometrial gene expression profile at the time of embryo implantation than women without endometriosis? SUMMARY ANSWER: The endometrial gene expression profile of women with endo…

article 2017
The Effect of Copper on Endometrial Receptivity and Induction of Apoptosis on Decidualized Human Endometrial Stromal Cells
Reproductive sciences (Thousand Oaks, Calif.) ·doi:10.1177/1933719117732165

Intrauterine devices (IUDs) have been widely used to prevent pregnancies with great efficacy during decades. It has been demonstrated that IUD alters the endometrial gene expression, but there is no scientific data about how copper, a metal…

2014
Guidelines for the design, analysis and interpretation of 'omics' data: focus on human endometrium.
Human reproduction update ·doi:10.1093/humupd/dmt048

Background'Omics' high-throughput analyses, including genomics, epigenomics, transcriptomics, proteomics and metabolomics, are widely applied in human endometrial studies. Analysis of endometrial transcriptome patterns in physiological and …

2013
MicroRNAs miR-30b, miR-30d, and miR-494 regulate human endometrial receptivity.
Reproductive sciences (Thousand Oaks, Calif.) ·doi:10.1177/1933719112453507

MicroRNAs (miRNAs) act as important epigenetic posttranscriptional regulators of gene expression. We aimed to gain more understanding of the complex gene expression regulation of endometrial receptivity by analyzing miRNA signatures of fert…

article 2011
Adenomyosis does not affect implantation, but is associated with miscarriage in patients undergoing oocyte donation
Fertility and sterility ·doi:10.1016/j.fertnstert.2011.07.1088

ObjectiveTo evaluate the effect of adenomyosis on endometrial gene expression and its correlation with clinical outcome.DesignTranscriptomic analysis of the endometrium of women with adenomyosis during the window of implantation. Retrospect…

2010
Human endometrial side population cells exhibit genotypic, phenotypic and functional features of somatic stem cells.
PloS one ·doi:10.1371/journal.pone.0010964

During reproductive life, the human endometrium undergoes around 480 cycles of growth, breakdown and regeneration should pregnancy not be achieved. This outstanding regenerative capacity is the basis for women's cycling and its dysfunction …

article 2010
The Protein Kinase A Pathway-Regulated Transcriptome of Endometrial Stromal Fibroblasts Reveals Compromised Differentiation and Persistent Proliferative Potential in Endometriosis
Endocrinology ·doi:10.1210/en.2009-0923

Intrinsic abnormalities in transplanted eutopic endometrium are believed to contribute to the pathogenesis of pelvic endometriosis. Herein we investigated transcriptomic differences in human endometrial stromal fibroblasts (hESFs) from wome…

article 2010
Unique Transcriptome, Pathways, and Networks in the Human Endometrial Fibroblast Response to Progesterone in Endometriosis
Biology of reproduction ·doi:10.1095/biolreprod.110.086181

Eutopic endometrium in endometriosis has molecular evidence of resistance to progesterone (P(4)) and activation of the PKA pathway in the stromal compartment. To investigate global and temporal responses of eutopic endometrium to P(4), we c…