Dottino P

No ORCID on file · 3 papers in corpus · active 2015-2018
2018
Detection of endometrial precancer by a targeted gynecologic cancer liquid biopsy.
Cold Spring Harbor molecular case studies ·doi:10.1101/mcs.a003269

Endometrial cancer is the most common gynecologic malignancy in industrialized countries, and both its incidence and its associated mortality are increasing. The "liquid biopsy" is becoming an important transformative precision oncology too…

2016
Genomic Analysis of Uterine Lavage Fluid Detects Early Endometrial Cancers and Reveals a Prevalent Landscape of Driver Mutations in Women without Histopathologic Evidence of Cancer: A Prospective Cross-Sectional Study.
PLoS medicine ·doi:10.1371/journal.pmed.1002206

BackgroundEndometrial cancer is the most common gynecologic malignancy, and its incidence and associated mortality are increasing. Despite the immediate need to detect these cancers at an earlier stage, there is no effective screening metho…

2015
Personalized Circulating Tumor DNA Biomarkers Dynamically Predict Treatment Response and Survival In Gynecologic Cancers.
PloS one ·doi:10.1371/journal.pone.0145754

BackgroundHigh-grade serous ovarian and endometrial cancers are the most lethal female reproductive tract malignancies worldwide. In part, failure to treat these two aggressive cancers successfully centers on the fact that while the majorit…