Dai H

ObjectiveThis retrospective cohort study aimed to evaluate whether a goal-directed weight loss intervention prior to assisted reproductive technology (ART) improves live birth rates compared with immediate in vitro fertilization (IVF) witho…

BackgroundTraditional research on the female reproductive tract (FRT) microbiome has focused on the dominance of bacteria, particularly Lactobacillus, as a marker of health. This bacteriocentric paradigm, however, cannot fully explain clini…

In clinical drug development, two fundamental questions must be addressed: what is the success rate of drugs in clinical trial; how does such rate change over time. Here, a dynamic strategy for calculating clinical trial success rate (ClinS…

In briefPreeclampsia is a severe pregnancy-related complication that can result in adverse maternal and fetal outcomes. Current therapeutic options for preeclampsia remain limited. This study demonstrates that epicatechin can inhibit pyropt…

The accelerating trend of obesity in women of childbearing age has become a significant issue in personal health, female fecundity, and offspring development. Simvastatin (SV) is a statin commonly prescribed oral agent for lipid-lowering th…

Shaofuzhuyu Decoction (SFZYD) is a classical formula for treating endometriosis of cold coagulation and blood stasis (ECB). The clinical efficacy is definite, but the potential mechanisms require further exploration. The study aimed to reve…

Endometriosis is a common disease of reproductive-age women and an important cause of dysmenorrhea and infertility. Information on endometriosis is complex and there is a lack of summarization of available results. The study aims to evaluat…

BackgroundAbdominal wall desmoid-type fibromatoses (AWDF) are occasionally encountered in clinical work, but related CT reports are rare, and most cases were misdiagnosed as malignant tumors.ObjectiveWe aimed to determine the diagnostic val…

BackgroundN6-methyladenosine (m6A) has been identified as the most common, abundant, and conserved internal transcriptional modification. Long noncoding RNAs (lncRNAs) are noncoding RNAs consisting of more than 200 nucleotides, and the expr…

ObjectiveTo investigate the profiles of the vaginal microbiome in patients with endometrial hyperplasia and to explore the potential value of vaginal microbiome in the diagnosis of endometrial hyperplasia. Materials/Methods. 26 patients suf…

AIM: The aim of this study was to investigate the expression of Forkhead box M1 (FoxM1) in endometriosis and determine FoxM1's possible effects on endometriotic epithelial cells (EECs) invasion and epithelial-mesenchymal transition (EMT). M…

This study aimed to study the expression of homeobox (HOX)A11-AS1 ( HOXA11 antisense RNA) long noncoding RNA (lncRNA) and the expression of homeobox A ( HOXA9, HOXA10, HOXA11, and HOXA13) genes in the eutopic (EU) and ectopic (EC) endometri…

PurposeTo describe the long noncoding RNA (lncRNA) profiles in cumulus cells isolated from polycystic ovary syndrome (PCOS) patients by employing a microarray and in-depth bioinformatics analysis. This information will help us understand th…

The present report aimed to study genetic alterations underlying extraovarian peritoneal serous papillary carcinoma (EPSPC), which have not previously been systematically investigated. A case of EPSPC was identified, and its genetic alterat…

BACKGROUND: The study was performed to characterize and compare the serum lipid profile in gynecologic cancers and benign diseases. MATERIALS AND METHODS: A total of 1,550 age-matched females were included in this study: 760 patients with g…

OBJECTIVES: To study the expression patterns of steroid receptor coactivators (SRC) and steroid-induced stromal cell-derived factor-1 (SDF-1) in endometriosis, and to explore the roles of SRC in the steroid-induced SDF-1 expression endometr…

AimTo investigate the expression of calcium channel protein in uterine fibroids, and to explore the relationship between calcium signaling pathway and the pathogenesis of uterine fibroids.MethodsUterine fibroid tissues (UFC) and adjacent he…

ObjectiveTo assess the long-term efficacy and quality of life associated with laparoscopic bilateral uterine artery occlusion plus partial resection of symptomatic adenomyosis.Study designA total of 182 eligible patients with symptomatic ad…

STUDY OBJECTIVE: To examine the clinical application of laparoscopic partial resection of symptomatic adenomyosis combined with uterine artery occlusion (UAO). DESIGN: Retrospective cohort study (Canadian Task Force classification III). S…