Si-Man Chen

No ORCID on file · 2 papers in corpus · active 2023-2025

Study types

  • other 2

Condition tags

  • endometriosis 2
other 2025
Creatine promotes endometriosis progression by inducing M2 polarization of peritoneal macrophages
Reproduction (Cambridge, England) ·doi:10.1530/REP-24-0278

IN BRIEF: Endometriosis (EM) is a chronic inflammatory disease with unclear pathogenesis, in which peritoneal macrophages play a pivotal role. This study demonstrates that creatine (CR) induces M2 polarization of peritoneal macrophages, pro…

other 2023
Heme induced progesterone-resistant profiling and promotion of endometriosis in vitro and in vivo
Biochimica et biophysica acta. Molecular basis of disease ·doi:10.1016/j.bbadis.2023.166761

Endometriosis is an estrogen-dependent, progesterone-resistant gynecological disease with an unknown pathogenesis. Compared to women without endometriosis, women with endometriosis have a remarkably high heme level in the peritoneal fluid. …