George C. Tseng

ORCID: 0000-0002-5447-1014 · 26 papers in corpus
preprint 2023
·doi:10.1158/1078-0432.c.6522953

AbstractPurpose: Mechanisms of immune dysregulation associated with advanced tumors are relatively well understood. Much less is known about the role of immune effectors against cancer precursor lesions. Endometrioid and clear-cell ovarian …

preprint 2023
·doi:10.1158/1078-0432.c.6522953.v1

AbstractPurpose: Mechanisms of immune dysregulation associated with advanced tumors are relatively well understood. Much less is known about the role of immune effectors against cancer precursor lesions. Endometrioid and clear-cell ovarian …

preprint 2023
·doi:10.1158/1078-0432.22455170

Supplementary Materials and Methods

preprint 2023
·doi:10.1158/1078-0432.22455170.v1

Supplementary Materials and Methods

preprint 2023
·doi:10.1158/1078-0432.22455191.v1

Suppl Fig S1. Venn diagram of DE genes from 3 group comparisons

preprint 2023
·doi:10.1158/1078-0432.22455191

Suppl Fig S1. Venn diagram of DE genes from 3 group comparisons

preprint 2023
·doi:10.1158/1078-0432.22455188.v1

Suppl Fig S2. Kras and Pten pathways in relationship to complement gene expression

preprint 2023
·doi:10.1158/1078-0432.22455188

Suppl Fig S2. Kras and Pten pathways in relationship to complement gene expression

preprint 2023
·doi:10.1158/1078-0432.22455185.v1

Suppl Fig S3. Antibody-mediated, complement-induced cytotoxicity

preprint 2023
·doi:10.1158/1078-0432.22455185

Suppl Fig S3. Antibody-mediated, complement-induced cytotoxicity

preprint 2023
·doi:10.1158/1078-0432.22455182.v1

Suppl Fig S4. Complement and non-target siRNA

preprint 2023
·doi:10.1158/1078-0432.22455182

Suppl Fig S4. Complement and non-target siRNA

preprint 2023
·doi:10.1158/1078-0432.22455179.v1

Suppl Table S1. Differentially expressed genes from different group comparisons

preprint 2023
·doi:10.1158/1078-0432.22455179

Suppl Table S1. Differentially expressed genes from different group comparisons

preprint 2023
·doi:10.1158/1078-0432.22455176.v1

Suppl Table S2. Top five canonical pathways from different group comparisons, identified via Ingenuity Pathway Analyses

preprint 2023
·doi:10.1158/1078-0432.22455176

Suppl Table S2. Top five canonical pathways from different group comparisons, identified via Ingenuity Pathway Analyses

preprint 2023
·doi:10.1158/1078-0432.22455173

Suppl Table S3. Top five networks from different group comparisons, identified via Ingenuity Pathway Analyses

preprint 2023
·doi:10.1158/1078-0432.22455173.v1

Suppl Table S3. Top five networks from different group comparisons, identified via Ingenuity Pathway Analyses

2022
Cancers ·doi:10.3390/cancers14225647

The immune tumor microenvironment (TME) of epithelial ovarian cancer (EOC) carries both effector and suppressive functions. To define immune correlates of chemotherapy-induced tumor involution, we performed longitudinal evaluation of biomar…

article 2018
·doi:10.1158/1557-3265.ovca17-b23

Abstract Objectives: To investigate changes in estrogen receptor–alpha (ERα) signaling during the progression of endometriosis to endometriosis-associated ovarian cancer (EAOC) as a putative driver of malignant transformation. Methods: We p…

2018
Frontiers in cellular and infection microbiology ·doi:10.3389/fcimb.2018.00307

Sexually transmitted infection (STI) of the upper reproductive tract can result in inflammation and infertility. A biomarker of STI-induced upper tract inflammation would be significant as many women are asymptomatic and delayed treatment i…

article 2018
Hormones & cancer ·doi:10.1007/s12672-018-0350-9

To investigate changes in estrogen receptor alpha (ERα) signaling during progression of endometriosis to endometriosis-associated ovarian cancer (EAOC) as a driver of malignant transformation. We procured tissue samples of normal endometriu…

article 2016
·doi:10.1016/j.ygyno.2016.04.305
article 2014
·doi:10.1158/1538-7445.am2014-1653

Abstract Introduction: Endometriosis is a largely benign, chronic inflammatory disease defined by the presence of endometrial-like glands surrounded by stroma. Epidemiologic studies suggest that endometriosis is an independent risk factor f…

article 2014
Clinical cancer research : an official journal of the American Association for Cancer Research ·doi:10.1158/1078-0432.ccr-14-1338

PURPOSE: Mechanisms of immune dysregulation associated with advanced tumors are relatively well understood. Much less is known about the role of immune effectors against cancer precursor lesions. Endometrioid and clear-cell ovarian tumors p…