Bruce R. Carr

No ORCID on file · 28 papers in corpus · active 1997-2019

Study types

  • article 20
  • review 4
  • rct 2
  • other 1

Condition tags

  • endometriosis 23
  • dysmenorrhea 4
  • chronic_pelvic_pain 4
  • infertility 2
  • dyspareunia 2
  • endometrioma 1
article 1998
Deficient 17β-Hydroxysteroid Dehydrogenase Type 2 Expression in Endometriosis: Failure to Metabolize 17β-Estradiol1
The Journal of clinical endocrinology and metabolism ·doi:10.1210/jcem.83.12.5301

Aberrant aromatase expression in stromal cells of endometriosis gives rise to conversion of circulating androstenedione to estrone in this tissue, whereas aromatase expression is absent in the eutopic endometrium. In this study, we initiall…

article 1998
Treatment of Severe Postmenopausal Endometriosis With an Aromatase Inhibitor
Fertility and Sterility ·doi:10.1016/s0015-0282(98)00022-3

ObjectiveTo treat an unusually aggressive case of recurrent postmenopausal endometriosis.DesignCase report.SettingUniversity of Texas Southwestern Medical Center (Dallas, Texas).Patient(s)A 57-year-old woman who presented with recurrent sev…

article 1997
Prostaglandin E2Stimulates Aromatase Expression in Endometriosis-Derived Stromal Cells1
The Journal of clinical endocrinology and metabolism ·doi:10.1210/jcem.82.2.3783

C19 steroids are converted to estrogens by aromatase P450 (P450arom). Aromatase expression in humans is regulated by use of tissue-specific promoters in the placenta (promoter I.1), adipose tissue (promoters I.4, I.3, and II), and gonads (p…