Vinay Shukla

ORCID: 0000-0002-6181-269X · 3 papers in corpus
2022
Acquisition of hypoxia inducibility by oxygen sensing N-terminal cysteine oxidase in spermatophytes
·doi:10.22541/au.165555187.70819978/v1

N-terminal cysteine oxidases (NCOs) use molecular oxygen to oxidize the amino-terminal cysteine of specific proteins, thereby initiating the proteolytic N-degron pathway. To expand the characterization of the plant family of NCOs (PCOs), we…

article 2021
Targeted inhibition of TAK1 abrogates TGFβ1 non-canonical signaling axis, NFκB/Smad7 inhibiting human endometriotic cells proliferation and inducing cell death involving autophagy
Cytokine ·doi:10.1016/j.cyto.2021.155700

Transforming growth factor (TGFβ) is known to play a major role in establishment and maintenance of endometriosis as reported by our group earlier, the underlying mechanism remains to be explored. We deciphered the involvement of TAK1 in TG…

2017
The regulation of Hh/Gli1 signaling cascade involves Gsk3β- mediated mechanism in estrogen-derived endometrial hyperplasia.
Scientific reports ·doi:10.1038/s41598-017-06370-1

The present study was undertaken to explore the functional involvement of Hh signaling and its regulatory mechanism in endometrial hyperplasia. Differential expression of Hh signaling molecules i.e., Ihh, Shh, Gli1 or Gsk3β was observed in …