Hester A

No ORCID on file · 3 papers in corpus · active 2020-2022
2022
Scientific reports ·doi:10.1038/s41598-022-05785-9

In recurrent epithelial ovarian cancer (EOC) most patients develop platinum-resistance. On molecular level the NRF2 pathway, a cellular defense mechanism against reactive oxygen species, is induced. In this study, we investigate AKR1C1/2, t…

2020
Journal of cancer research and clinical oncology ·doi:10.1007/s00432-020-03241-7

PurposeThyroid hormone receptors (THR) have manifold functions and are involved in the carcinogenesis of several tumor types. Within this study, we aimed to investigate the expression pattern (nuclear versus cytoplasmic) of the THR alpha an…

2020
Histochemistry and cell biology ·doi:10.1007/s00418-020-01873-x

Several risk factors like obesity and hyperlipidemia were described for endometrial cancer. Here, the nuclear NAD-dependent histone-deacetylase Sirtuin1 (SIRT1) seems to be important. SIRT1 is also involved in cell regulatory mechanisms and…