Song Y

PURPOSE: To identify the specific risk factors associated with unexplained infertility (UI) among infertile couples. METHODS: We conducted a retrospective cohort study analyzing UI risk factors, focusing on 5465 infertile couples who compl…

Endometriosis is a common gynecologic disorder that can be considered in two major categories based on whether the endometrium invades the myometrium: adenomyosis, in which the endometrial glands and mesenchyme migrate into the myometrium, …

Yaan Song,1– 5,* Yiqing Lin,1– 5,* Ming Yuan,1– 5 Ye Cao,1– 5 Guoyun Wang1– 5 1Department of Obstetrics and Gynecology, Shandong Provincial Hospital, Shandong University, Jinan, Shandong, People’s Republic of China; 2Medical Integra…

BACKGROUND: Appendiceal adenocarcinoma (AA) is a rare gastrointestinal cancer that frequently presents with peritoneal metastases; the standard of care for resectable peritoneal metastases from AA limited to the peritoneum is cytoreductive …

OBJECTIVE: To investigate the effect of cheek acupuncture therapy combined with Chinese herbal medicine on chronic pelvic pain (CPP) in female patients. METHODS: Female patients with CPP treated with cheek acupuncture (CA) and Chinese herb…

BACKGROUND: Sexually transmitted infections (STIs) contribute to female infertility by causing pelvic inflammatory disease (PID) and fallopian tube damage. Utilizing the Global Burden of Disease (GBD) database, we aim to comprehensively eva…

BACKGROUND: Ovarian endometriomas impair ovarian reserve and fertility in women of reproductive age. Ethanol sclerotherapy is a fertility-preserving alternative to surgery. Nonetheless, predicting cumulative live birth rates after in vitro …

RESEARCH QUESTION: Is surgery effective in decreasing iron deposition in the ovarian tissue surrounding an ovarian endometrioma? DESIGN: This cohort study was conducted in China between July 2023 and April 2024. Seventy-nine patients with …

Abstract Background Symptom recurrence remains a clinically significant concern, highlighting the need for reliable prognostic markers to guide patient management. This study focused on evaluating the association of the maximum junction…

Acute severe joint pain is a major symptom in gouty arthritis (GA), and its adequate treatment represents an unmet medical need. Mrgprb2, a specific mast cell receptor, has been implicated in the generation of chronic pain by mobilizing mas…

Recent studies have highlighted the crucial role of mechanical properties in the ovarian microenvironment for ovarian function. However, the mechanisms that cause ovarian matrix stiffening during aging remain incompletely understood. Here w…

INTRODUCTION: NR5A1 variants are among the most frequent monogenic causes of disorders of sex development (DSD). However, genotype-phenotype correlations remain unclear, and oligogenic contributions to variability are underexplored in non-c…

Endometriosis (EMS) remains understudied in effective management strategies. The interplay between macrophage dysfunction and microbiota-derived immune signals emerges as a potential mechanism in EMS pathogenesis, suggesting its relevance f…

BACKGROUND: Pro-EGCG has shown therapeutic promise for endometriosis, yet its immunoregulatory mechanisms remain unclear. Myeloid-derived suppressor cells (MDSCs) are key drivers of disease progression. This study investigates whether Pro-E…

Endometriosis-associated ovarian cancer (EAOC) is a rare subtype of ovarian cancer arising from the malignant transformation of endometriosis (EMS). Despite growing clinical awareness, its underlying pathogenic mechanisms are not fully unde…

OBJECTIVE: To screen immune-related biomarkers in diagnosing patients with both endometriosis (EM) and systemic lupus erythematosus (SLE). METHODS: After performing differential expression analysis, immune infiltration analysis, WGCNA, the…

BACKGROUND: Tumor necrosis factor (TNF) plays a prominent role in endometriosis research, but the evolution and current status of this field have not been systematically mapped. METHODS: This bibliometric study systematically analyzed publ…

Y-box binding protein 1 (YBX1) has been reported to play a role in human granulosa cell (GC) dysfunction by binding with long noncoding RNAs in patients with primary ovarian insufficiency (POI). 5-Methylcytosine (m5C) methylation is an abun…

BACKGROUND: There is limited research about the pregnancy outcomes of POSEIDON group 2 patients. This study aims to evaluate the factors related to the clinical outcomes of in vitro fertilization (IVF) and/or intracytoplasmic sperm injectio…

Endometriosis is a chronic inflammatory disease with limited screening options and a recognized diagnostic delay. To investigate detection potentialities, a bioelectronic sensor is realized to detect endometriotic vs endometrial models via …

BACKGROUND: Endometriosis is a chronic gynecological disorder characterized by the presence of endometrial-like tissue outside the uterine cavity, causing chronic pain and infertility. Hypoxia plays a significant role in the progression of …

AIM: Adenomyosis and endometriosis are gynecological conditions with overlapping symptoms but distinct pathologies. Both affect the women's reproductive system, but their interrelation and shared clinical pathways are underexplored. This st…

Ovarian clear cell carcinoma (OCCC) is a subtype of ovarian cancer with a poor prognosis that often shows resistance to chemotherapy. This study retrospectively analyzed 247 patients with OCCC who were admitted to the Cancer Hospital of the…

This network meta-analysis aims to identify the best possible combination therapy for individuals suffering from adenomyosis. To identify pertinent research for the network meta-analysis, a comprehensive search was conducted across multiple…