Paolo Macor

ORCID: 0000-0003-3079-4019 · 2 papers in corpus

lab-animal 2021

The Inflammatory Feed-Forward Loop Triggered by the Complement Component C3 as a Potential Target in Endometriosis

Frontiers in immunology ·doi:10.3389/fimmu.2021.693118

The complement system is a major component of humoral innate immunity, acting as a first line of defense against microbes via opsonization and lysis of pathogens. However, novel roles of the complement system in inflammatory and immunologic…

lab-animal 2020

Complement Component 3 expressed by the endometrial ectopic tissue is involved in the endometriotic lesion formation through mast cell activation

·doi:10.1101/2020.11.19.389536

Abstract The pathophysiology of endometriosis (EM) is an excellent example of immune dysfunction, reminiscent of tumor microenvironment as well. Here, we report that an interplay between C3 and mast cells (MCs) is involved in the pathogenes…