Zhang L

BACKGROUND: Robotic liver resections (RLRs) are increasingly performed worldwide. The IWATE criteria offer a standardized classification to correlate the complexity of these procedures with surgical outcomes. This study analyzes a single su…

Objective: To analysis the safety and feasibility of laparoscopic total hysterectomy in patients with obliterated rectouterine pouch. Methods: A retrospective analysis was conducted on 197 patients who underwent laparoscopic total hysterect…

Ovarian cancer (OC) is a deadly disease and lacks a precise marker for diagnosis worldwide. Our previous work has shown the overexpression of flotillin-1 (FLOT1) in OC tissue. To improve diagnostic sensitivity and accuracy, we evaluated the…

BACKGROUND: Gasless transvaginal natural orifice transluminal endoscopic surgery (G-vNOTES) can avoid complications related to pneumoperitoneum, but there is limited research on G-vNOTES. Here, we aimed to compare the hemodynamic profiles a…

PURPOSE: Ovarian endometriosis, a prevalent condition in reproductive-age women, causes dysmenorrhea and infertility, significantly impairing quality of life. To date, there is no systematic description of ovarian endometriosis in the liter…

Xian Wu,1,* Xia Yu,2,* Lu Yang,1,* Aijie Xie,1 Yunyi Su,1 Ling Zhang,1 Yonghong Lin,1 Xiaoqin Gan1 1Department of Obstetrics and Gynecology, Chengdu Women’s and Children’s Central Hospital, School of Medicine, University of Elec…

BACKGROUND: Dysmenorrhea is a prevalent gynecological disorder with multifactorial pathophysiology, including prostaglandin overproduction, inflammation, and pain sensitization. Emerging evidence suggests that gut microbiota may contribute …

Abstract Introduction Endometriosis (EMS) is an estrogen-dependent inflammatory disorder characterized by immune dysregulation. This condition profoundly affects the quality of life and reproductive health of nearly 200 million women of rep…

BACKGROUND: Chat-Generative Pretrained Transformer (ChatGPT) has proven its value in medical information acquisition and perioperative education. This study aimed to evaluate correlated factors to explore the value of ChatGPT in patient com…

Endometriosis is one of the most common, difficult, and complicated gynecological disorders. The present study investigated the expression of HOXC6 in endometriosis and described its possible role in its pathogenesis. Ectopic and eutopic en…

Endometriosis (EM) is a common chronic gynaecological disease that affects 10% of women of reproductive age globally. EM is defined as the presence of endometrial glands and stroma in extrauterine locations, and it can result in pelvic pain…

PURPOSE: Endometriosis (EM) and recurrent spontaneous abortion (RSA) exhibit clinical associations, yet their shared molecular mechanisms remain unclear. This study aimed to identify shared molecular mechanisms and potential hub genes under…

Human genetics supports a causal involvement of IL-6 signaling in atherosclerotic cardiovascular disease, prompting the clinical development of anti-IL-6 therapies. Genetic evidence has historically focused on IL6R missense variants, but em…

BACKGROUND: Approximately 50% of the women with polycystic ovary syndrome (PCOS) are overweight or obese and obesity can significantly impair reproductive function. This study aimed to investigate the association between body mass index (BM…

OBJECTIVE: To evaluate the impact of endometrial polyps (EP) on postoperative pregnancy outcomes in infertile women with endometriosis (EMs). METHODS: PubMed, Embase, The Cochrane Library, CNKI, VIP, SinoMed, and WanFang Data databases wer…

OBJECTIVE: IVF/ICSI is associated with an increased risk of placenta accreta spectrum disorders (PAS). Invasive PAS can result in significant adverse maternal and fetal outcomes. This study investigates the impact of IVF/ICSI on the severit…

Endometriosis (EM) is a chronic, estrogen-dependent disease characterized by the ectopic presence of endometrial-like tissue. Despite extensive research, its molecular pathogenesis remains unclear. In this study, we conducted an integrated …

Infertility poses considerable challenges to both the endocrine system and psychological well-being of affected women. In particular, those undergoing Assisted Reproductive Technology (ART) confront not only physiological demands but also s…

Aspartame is a nonnutritive sweetener derived from phenylalanine and is widely used in food and beverages globally. In recent years, its safety, particularly the potential carcinogenic risks, has garnered significant attention; however, the…

Neuropathic pain (NP) is caused by primary damage and dysfunction of nervous system, in which spinal cord injury (SCI) is a common cause of NP. Evidence shows that neuroinflammation and oxidative stress are related to the pathophysiology of…

BACKGROUND: The incidence and fatality rates of chronic obstructive pulmonary disease (COPD) are increasing, and the acute exacerbation of COPD (AECOPD) causes poor prognosis in patients. AIM: This study evaluated the clinical role of seru…

The periconception period is critical for embryo development, pregnancy outcomes, and offspring health. During this stage, oviductal and uterine fluids facilitate embryo-maternal interactions and support early embryonic development. Using P…

OBJECTIVE: The high post-surgery recurrence rate of endometriosis (EMs) has emerged as a challenge in the long-term manaagement of the condition. This study is aimed at investigating the mechanisms of Neiyiting (NYT) decoction in preventing…

PURPOSE: This study aimed to investigate the impact of obstructive sleep apnea (OSA) on in vitro fertilization (IVF) and embryo transfer outcomes in infertile patients with polycystic ovary syndrome (PCOS). METHODS: We conducted a prospect…