Chen X

BackgroundThe adnexal region in females presents complex imaging due to the menstrual cycle. Accurate diagnosis is crucial for effective tumor treatment. This study aims to assess the clinical utility of abnormal adnexal uptake on 68Ga-FAPI…

Abstract Objective To identify risk factors for postoperative pelvic–abdominal infection after total laparoscopic hysterectomy in patients with benign gynecological diseases and to develop and validate a clinically applicable prediction m…

Endometrial cancer (EC) incidence is rising, yet current diagnostics lack precision and scalability. We develop an artificial intelligence (AI)-based platform integrating multi-biofluid omics and clinical data for EC stratification. Using t…

Pelvic inflammatory disease (PID), a prevalent gynecological ailment compromising women's health, demonstrates established risk mitigation from dietary trace minerals. However, iron's role in PID pathogenesis remains unestablished. The Nati…

BackgroundOvarian clear cell carcinoma (OCCC) is a rare aggressive, and chemo-resistant subtype of epithelial ovarian cancer. Current limitations in precisely characterizing its molecular features have resulted in restricted availability of…

BackgroundThe follicular-phase long GnRHa protocol is a common protocol in COH. This study mainly analyzed the recovery of FSH levels on the day of Gn initiation compared with basal FSH levels on the day of downregulation and studied the co…

ObjectiveThe aim of this study was to compare the therapeutic efficacy of integrating virtual reality technology with conventional pelvic floor rehabilitation therapy versus conventional therapy alone in postpartum women with myofascial pel…

ObjectiveTo identify risk factors for recurrence after hysteroscopic endometrial polypectomy, with particular emphasis on postoperative pathological features (endometrial hyperplastic changes) and potential protective role of medical therap…

BACKGROUND: Endometriosis (EMs) is a chronic enigmatic gynecological disorder which pathogenesis have not been fully elucidated. Exosomes have been proven to participate in endometriosis. However, the role of exosomes in the pathogenesis of…

BackgroundSyndrome differentiation in Traditional Chinese Medicine (TCM) is pivotal to clinical practice and dictates the efficacy of medicinal treatments. However, precision diagnostic models for TCM syndromes, constructed from biomarkers …

ObjectivesThis study aims to evaluate the safety and efficacy of ovarian vein embolization combined with polidocanol sclerotherapy for Venous-origin chronic pelvic pain (VO-CPP) and to elucidate potential risk factors affecting prognosis.Me…

BACKGROUND: Endometriosis (EMs) is a chronic inflammatory disease characterized by tumor-like growth behavior and limited therapeutic options. Increasing evidence suggests that gut microbiota may contribute to EMs progression by promoting c…

BACKGROUND: The specific gut microbial signatures and their correlation with immune-inflammatory markers in infertile women with endometriosis remain underexplored.To investigate the differences in gut microbiota and their associations with…

BackgroundEndometrial intrauterine adhesions (IUA) arise due to comprised regenerative capacity of endometrium and aberrant fibrotic processes. These adhesions significantly affect fertility by impeding embryo implantation, sustaining pregn…

Endometriosis is a common gynecological disorder in which inflammatory and immune responses play a crucial role in its development and progression. This study aimed to identify potential inflammation-related biomarkers for the diagnosis and…

BackgroundThe cytokines interleukin (IL)-6 and transforming growth factor-beta (TGF-β) are established inducers of pathogenic T helper 17 (Th17) cells from naïve T cells. In the maternal-fetal compartment, IL-6 signaling elevates levels of …

BACKGROUND: Chronic pain resulting from postoperative adhesions represents a significant clinical concern due to its substantial impact on patient quality of life; however, optimal therapeutic management remains contentious. This systematic…

ObjectiveTo compare the therapeutic effects of laparoscopic recanalization and laparotomy recanalization on tubal patency restoration after tubal sterilization.MethodsA retrospective analysis was conducted on the clinical data of 122 patien…

BackgroundPreeclampsia is a severe hypertensive disorder with rising global prevalence. While machine learning (ML) models for predicting preeclampsia are increasingly published, existing evidence shows high heterogeneity, and the distincti…

Unexplained recurrent pregnancy loss (URPL) represents a prevalent obstetric complication and remains a challenging condition with poorly understood genetic etiology. Through whole-exome sequencing of 94 URPL patients, we identified enriche…

BACKGROUND: Endometriosis (EMS) is characterized by pain symptoms that seriously affect patients' quality of life. Gut microbiome-related metabolites (GMRM) play an important role in the process of EMS. However, the role of GMRM in endometr…

Wen Shi,1– 3,* Minyi Wang,1– 3,* Zhuang Jin,1– 3 Xiaochuan Chen,1– 3 Jinbo Li,1– 3 Huiling Lai,1– 3 Xiao Li,1– 3 Qiyu Zhong,1– 3 Ye Chen,1– 3 Shuqin Chen1– 3 1Department of Gynecology, The Sixth Affiliated Hospital, Sun Yat-sen Univ…

Wen Shi,1–3,* Minyi Wang,1–3,* Zhuang Jin,1–3 Xiaochuan Chen,1–3 Jinbo Li,1–3 Huiling Lai,1–3 Xiao Li,1–3 Qiyu Zhong,1–3 Ye Chen,1–3 Shuqin Chen1–3 1Department of Gynecolog…

BackgroundThe single-incision laparoscopic cholecystectomy (SILC) achieves a scarless appearance through a single umbilical approach. However, the restricted surgical field of view, frequent instrument collisions limit its clinical applicab…