Fennema JS

No ORCID on file · 2 papers in corpus · active 2005-2009
2009
TLR9 KO mice, haplotypes and CPG indices in Chlamydia trachomatis infection.
Drugs of today (Barcelona, Spain : 1998) ·doi:10.1358/dot.2009.45.2.1322478

Previous studies have investigated the role of Toll-like receptor (TLR)2 and TLR4 in susceptibility to and severity of Chlamydia trachomatis infections. In this study we employ a unique integrated approach to study the role of the intracell…

2005
The CD14 functional gene polymorphism -260 C>T is not involved in either the susceptibility to Chlamydia trachomatis infection or the development of tubal pathology.
BMC infectious diseases ·doi:10.1186/1471-2334-5-114

BackgroundThe functional polymorphism -260 C>T in the LPS sensing TLR4 co-receptor CD14 gene enhances the transcriptional activity and results in a higher CD14 receptor density. Individuals carrying the T/T genotype also have significantly …