C A Witz

The aim of this study was to investigate whether peroxisome proliferator-activated receptor (PPAR)-gamma activation has an effect on the attachment of endometrial cells to peritoneal mesothelial cells in a well-established in vitro model of…

OBJECTIVE: To evaluate the role of hyaluronic acid in the attachment of endometrial cells to mesothelium. DESIGN: In vitro study of adhesion of endometrial stromal and epithelial cells to mesothelial cells. SETTING: University medical cen…

ObjectiveTo evaluate the initial adhesion of endometrium to the peritoneum.DesignDescriptive study using light and confocal laser-scanning microscopy, immunohistochemistry, and transmission electron microscopy.SettingUniversity-based labora…

ObjectiveTo localize alpha2beta1 and alpha3beta1 integrins in the cell membrane of peritoneal mesothelium in vivo and in vitro.DesignDescriptive study using confocal and two-photon laser-scanning microscopy.SettingUniversity-based laborator…

ObjectiveTo determine whether whole fragments of endometrium can adhere to peritoneum with intact mesothelium.DesignTissue culture and immunohistochemical study.SettingUniversity medical center.Patient(s)Reproductive-age women undergoing su…

OBJECTIVE: To characterize the expression of alpha subunits of integrin adhesion molecules in peritoneal tissue in vivo and in vitro. METHOD: Peritoneum from the anterior abdominal wall (n = 22) and the serosa of the posterior uterus (n = …

There are many hypotheses concerning the pathogenesis of endometriosis, though no single theory can explain all cases. It is likely that several mechanisms are involved. Early studies concentrated on the histogenesis of the endometriotic le…

PROBLEM: Numerous studies have characterized the lymphocyte subpopulations in normal eutopic endometrium and suggested a role for the cytokine secretory products of these lymphocytes in regulating endometrial cell proliferation and differen…