Unno N

No ORCID on file · 12 papers in corpus · active 2005-2022

Study types

  • article 9
  • other 2

Condition tags

  • endometriosis 10
  • mesh:D004716 1
  • endometrioma 1
  • adenomyosis 1
2022
Gynecology and Minimally Invasive Therapy ·doi:10.4103/gmit.gmit_9_22

For preparing the optimal condition in transcervical resection (TCR) surgery, gonadotropin-releasing hormone (GnRH) agonist has been utilized. Recently, an oral GnRH antagonist (relugolix) is available and acts directly on GnRH receptor, av…

article 2021
Scientific reports ·doi:10.1038/s41598-020-79578-3

In endometriosis, M2 MΦs are dominant in endometriotic lesions, but the actual role of M2 MΦ is unclear. CD206 positive (+) MΦ is classified in one of M2 type MΦs and are known to produce cytokines and chemokines. In the present study, we u…

article 2021
Journal of gynecology obstetrics and human reproduction ·doi:10.1016/j.jogoh.2021.102114

INTRODUCTION: Although various perinatal complications have been reported to be increased in the pregnant patients with adenomyosis, it is not clear what type of patients with adenomyosis is more likely to cause obstetric complications. In …

article 2021
Biomedicines ·doi:10.3390/biomedicines9111519

Sphingosine 1-phosphate (S1P), an inflammatory mediator, is abundantly contained in red blood cells and platelets. We hypothesized that the S1P concentration in the peritoneal cavity would increase especially during the menstrual phase due …

other 2020
Reproductive sciences (Thousand Oaks, Calif.) ·doi:10.1007/s43032-019-00090-9

In endometriosis, M2 macrophages (MΦ) are dominant and promote the development of endometriosis lesions. However, the factor(s) which induces M2 MΦ are unknown. In the present study, we focused on interleukin (IL)-33, known as an alarmin an…

article 2020
Journal of cellular and molecular medicine ·doi:10.1111/jcmm.15823

Abstract Neuroimmune interactions are involved in the development of endometriosis. Here, we examined the role of a neuropeptide, calcitonin gene–related peptide (CGRP), and its receptor, receptor activity–modifying protein (RAMP) 1, in gro…

article 2020
Journal of pharmacological sciences ·doi:10.1016/j.jphs.2020.05.003

Lymphangiogenesis is related to the growth of endometriosis. Here, we examined whether vascular endothelial growth factor (VEGF) receptor 1 (VEGFR1) signaling plays a role in lymphangiogenesis during endometriosis. Endometrial fragments fro…

article 2020
Biomedicines ·doi:10.3390/biomedicines8110467

Background: Relaxin (RLX)-2, produced by the corpus luteum and placenta, is known to be potentially effective in fibrotic diseases of the heart, lungs, kidneys, and bladder; however, its effectiveness in endometriosis has not yet been inves…

article 2019
Journal of Obstetrics and Gynaecology Research ·doi:10.1111/jog.14157

AIM: The aim of this study was to investigate the efficacy of T2 star (T2*) mapping in diagnosing ovarian cysts/ tumors. METHODS: diameter circle, was set as much as possible inside ovarian tumors/cysts to measure T2*values, and mean T2* va…

article 2019
Scientific reports ·doi:10.1038/s41598-019-43185-8

Abstract Angiogenesis is critical in maintenance of endometrial tissues. Here, we examined the role of VEGF receptor 1 (VEGFR1) signaling in angiogenesis and tissue growth in an endometriosis model. Endometrial fragments were implanted into…

article 2010
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie ·doi:10.1016/j.biopha.2010.12.008

Endometriosis is one of the most common gynecological diseases in women of reproductive age. Although cyclooxygenase (COX)-2 inhibitors are effective in the treatment of endometriosis, the adverse cardiovascular effects associated with thes…

other 2005
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie ·doi:10.1016/j.biopha.2005.05.005

Expression of receptors for prostaglandin (PG) and leukotriene (LT) has been reported to detect in endometrium and smooth muscle of uterus, suggesting involvement of these arachidonic metabolites in endometrial pathology and reproductive bi…