Ziyu Zhang

No ORCID on file · 14 papers in corpus · active 2018-2025

Study types

  • article 11
  • preprint 2
  • other 1

Condition tags

  • endometriosis 10
  • adenomyosis 5
  • disambig:endometritis 1
preprint 2025
Contrastive Learning-Guided Multiple Instance Learning for Automated Diagnosis of Chronic Endometritis from Digitized Histopathology
·doi:10.2139/ssrn.5766402
article 2024
Iron overload increases the sensitivity of endometriosis stromal cells to ferroptosis via a PRC2-independent function of EZH2
The international journal of biochemistry & cell biology ·doi:10.1016/j.biocel.2024.106553

Given the high concentration of iron in the micro-environment of ovarian endometriosis, it is plausible to hypothesize that ectopic endometrial cells may be more susceptible to undergoing ferroptosis. Manipulation of ferroptosis has been ex…

article 2024
Oestrogen promotes the progression of adenomyosis by inhibiting CITED2 through miR-145
Reproductive biomedicine online ·doi:10.1016/j.rbmo.2024.104108
article 2022
miR-218-5p in endometrial microenvironment prevents the migration of ectopic endometrial stromal cells by inhibiting LASP1
Reproductive biology and endocrinology : RB&E ·doi:10.1186/s12958-022-00928-z

BACKGROUND: Our previous two-dimensional electrophoresis experiment showed that the expression of LASP1 in patients with endometriosis was significantly higher than that of control endometrium. However, the molecular mechanism by which LASP…

article 2022
Whole-exome sequencing and functional validation reveal a rare missense variant in MMP7 that confers ovarian endometriosis risk
Human molecular genetics ·doi:10.1093/hmg/ddac062

Prior studies have shown that genetic factors play important roles in ovarian endometriosis. Herein, we first analyzed the whole-exome sequencing data from 158 patients with ovarian endometriosis and 385 local control women without endometr…

article 2021
ITRAQ-based proteomics analysis of tanshinone IIA on human ectopic endometrial stromal cells of adenomyosis
Archives of gynecology and obstetrics ·doi:10.1007/s00404-020-05936-1
preprint 2021
miR-218-5p in Endometrial Microenvironment Prevents the Migration of Ectopic Endometrial Stromal Cells by Inhibiting LASP1
·doi:10.21203/rs.3.rs-600354/v1

Abstract Our previous two-dimensional electrophoresis experiments showed that the expression of LASP1 in patients with endometriosis was significantly higher than that of control endometrium. However, the molecular mechanism by which LASP1 …

article 2020
Novel MYH8 mutations in 152 Han Chinese samples with ovarian endometriosis
Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology ·doi:10.1080/09513590.2020.1751107

Endometriosis is a common gynecological disease affecting up to 10% of women at reproductive age. Prior combined studies implied that MYH8 mutations might exist in endometriosis. Here, 152 Han Chinese samples with ovarian endometriosis were…

article 2020
Suppression of PRDX4 inhibits cell proliferation and invasion of ectopic endometrial stromal cells in endometriosis
Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology ·doi:10.1080/09513590.2020.1768369

Oxidative stress (OS) has been proposed to play a role in the development of EMs. Peroxiredoxins are a family of antioxidant proteins that exhibit peroxidase activity in a thioredoxin-dependent manner, protecting cells against OS. The Weste…

article 2019
Inhibition of formin like 2 promotes the transition of ectopic endometrial stromal cells to epithelial cells in adenomyosis through a MET-like process
Gene ·doi:10.1016/j.gene.2019.06.003
article 2018
Analysis of CARD10 and CARD11 somatic mutations in patients with ovarian endometriosis
Oncology letters ·doi:10.3892/ol.2018.8659

Endometriosis is a complex and heterogeneous pre-malignant inflammatory disease harboring multiple gene mutations. Previous studies have suggested that caspase recruitment domain family member (CARD)10 and CARD11 mutations may exist in endo…

other 2018
GZFLW Induces Apoptosis of Ectopic Endometrial Stromal Cells via Promoting VPS53 Protein Stability
Evidence-based complementary and alternative medicine : eCAM ·doi:10.1155/2018/1293630

Endometriosis is still a major problem in obstetrics and gynecology. While GZFLW (Gui Zhi Fu Ling Wan) has been originally used for treating gynecological diseases, however, the molecular mechanism that GZFLW acts on endometriosis is not cl…

article 2018
Mutation analysis of ZP1, ZP2, ZP3 and ZP4 genes in 152 Han Chinese samples with ovarian endometriosis
Mutation research ·doi:10.1016/j.mrfmmm.2018.12.003
article 2018
The presence of KRAS, PPP2R1A and ARID1A mutations in 101 Chinese samples with ovarian endometriosis
Mutation research ·doi:10.1016/j.mrfmmm.2018.03.001