Chen L

ORCID: 0009-0007-6042-463X · 324 papers in corpus
2022
Frontiers in endocrinology ·doi:10.3389/fendo.2022.881983

BackgroundPredicting the number of oocytes retrieved (NOR) following controlled ovarian stimulation (COS) is the only way to ensure effective and safe treatment in assisted reproductive technology (ART). To date, there have been limited stu…

article 2022
Zhonghua fu chan ke za zhi ·doi:10.3760/cma.j.cn112141-20220126-00050

Objective: To investigate the role of adenosine diphosphate ribosylation factor 6 (Arf6) in the pathogenesis of endometriosis. Methods: Endometrial tissues were sampled from women who were hospitalized in the Affiliated Hospital of Medical …

2022
JAMA network open ·doi:10.1001/jamanetworkopen.2022.36609

ImportanceThere is a lack of information regarding the need to postpone conception after COVID-19 vaccination.ObjectiveTo investigate the time interval between the first dose of inactivated COVID-19 vaccine and in vitro fertilization (IVF) …

other 2022
Frontiers in immunology ·doi:10.3389/fimmu.2022.944683

BACKGROUND: Endometriosis (EM) is a common gynecological disorder that often leads to irregular menstruation and infertility. The pathogenesis of EM remains unclear and delays in diagnosis are common. Thus, it is urgent to explore potential…

2022
International journal of women's health ·doi:10.2147/ijwh.s350768

Septate uterus with duplicate cervices and double vagina is a rare Müllerian duct anomaly mostly found in labor or gynecological examination. We present a case of a 40-year-old asymptomatic parous patient diagnosed with double cervix and co…

article 2022
Reproductive biology ·doi:10.1016/j.repbio.2022.100667

Recent evidence indicates that circular RNAs (circRNAs) play crucial regulatory roles in the pathogenesis and development of endometriosis. Circ_0004712 was found to be differentially expressed in endometriosis. However, the detailed functi…

2022
Journal of healthcare engineering ·doi:10.1155/2022/5319172

ObjectiveTo explore the clinical efficacy of assisted reproductive technology (ART) combined with progesterone capsules in the treatment of infertility caused by the diminished ovarian reserve (DOR) and its influence on serum FSH, E2, and L…

2022
American journal of translational research

ObjectiveTo explore the difference in clinical efficacy and safety of transvaginal and transumbilical single port laparoscopy for endometrial cancer.MethodsWe retrospectively included 100 endometrial cancer patients who were admitted to the…

2022
Trials ·doi:10.1186/s13063-022-06675-1

BackgroundAcupuncture or moxibustion has been proven to be effective for patients with primary dysmenorrhea (PDM). However, the respective advantages and potential central mechanism of acupuncture and moxibustion are worthy of investigating…

2022
Journal of oncology ·doi:10.1155/2022/5283388

We aim to investigate the correlation between the expression of estrogen-related receptor γ (ERRγ) and endometrial cancer (EC) progression and to evaluate the potential of ERRγ as a new biomarker for EC diagnosis. We analyzed the ERRγ expre…

article 2022
Clinical Radiology ·doi:10.1016/j.crad.2022.09.117

AIM: To investigate the value of amide proton transfer weighted (APTw) imaging and R2∗ mapping of cystic fluid in differentiating ovarian endometriotic cysts (OE) from other ovarian cystic (OOC) lesions. MATERIALS AND METHODS: A total of 4…

preprint 2022
·doi:10.21203/rs.3.rs-1919429/v1

Abstract Purpose Although numerous studies have attempted to establish the relationship between adenomyosis and infertility, no consensus has emerged. Our aim was to investigate whether adenomyosis and endometriosis affected IVF outcomes in…

2022
Reproductive health ·doi:10.1186/s12978-022-01459-x

BackgroundWith the implementation of the two-child policy in China, more couples have expressed the desire to have another child. We conducted this study to evaluate the incidence of infertility and risk factors in couples intending to have…

2022
Frontiers in oncology ·doi:10.3389/fonc.2022.1030246

BackgroundUterine corpus endometrial carcinoma (UCEC) is the third most common gynecologic malignancy. Fatty acid metabolism (FAM) is an essential metabolic process in the immune microenvironment that occurs reprogramming in the presence of…

article 2022
Journal of Minimally Invasive Gynecology ·doi:10.1016/j.jmig.2022.03.002
article 2022
Journal of gynecology obstetrics and human reproduction ·doi:10.1016/j.jogoh.2022.102349

BackgroundAdenomyosis refers to a pathological damage resulting from local and diffuse lesions in endometrium, caused by invasive endometrial gland and its mesenchyme. Our study aimed to reveal miR-183's role in the development of adenomyos…

2022
Frontiers in endocrinology ·doi:10.3389/fendo.2022.900829

ObjectivePredictive models of the cumulative live birth (CLB) in women undergoing in vitro fertilization (IVF) treatment are limited. The aim of this study was to develop and validate a nomogram for the CLB in women undergoing the first IVF…

2022
American journal of obstetrics and gynecology ·doi:10.1016/j.ajog.2021.11.027

BackgroundIn recent years, the issue of out-of-network billing for privately insured patients has been highlighted as a source of unexpected out-of-pocket charges for patients, even in the setting of an in-network primary surgeon. The Congr…

article 2022
Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS) ·doi:10.1016/j.jtemb.2022.127017

OBJECTIVE: The purpose of this study was to investigate iron metabolism indices in ovarian endometriosis (OEMs) and to demonstrate the potential clinical implications in the initiation and development of OEMs. METHODS: Three datasets in Ge…

2022
Frontiers in endocrinology ·doi:10.3389/fendo.2022.870708

PurposeThis study aimed to develop a risk prediction of fertilization disorders during the in vitro fertilization/intracytoplasmic sperm injection (IVF/ICSI).MethodsA retrospective study was performed with 106,728 fresh embryo IVF/ICSI cycl…

preprint 2022
·doi:10.21203/rs.3.rs-2329900/v1

Abstract Purpose : These study aims to assess the impact of endometrioma on patients who undergo ART treatment due to endometriosis. Methods : Retrospective study was conducted in women ≤ 40 years of age who underwent ART treatment at an ac…

2022
Frontiers in endocrinology ·doi:10.3389/fendo.2022.900499

BackgroundConceptions following in vitro fertilization (IVF) or intracytoplasmic sperm injection (ICSI) have an increased risk of congenital anomalies. Few studies have explored the prognosis of fetuses with congenital anomalies. This study…

other 2022
Frontiers in immunology ·doi:10.3389/fimmu.2022.945504

BACKGROUND: Adenomyosis is an estrogen-dependent gynecological disease. The pathogenesis of chronic pain, the main clinical symptom of adenomyosis, remains undefined. As a combination lymphocyte with both T-cell and natural killer (NK)-cell…

2022
Cell discovery ·doi:10.1038/s41421-022-00445-8

Gallbladder carcinoma (GBC) is the most common biliary tract malignancy with the lowest survival rate, primarily arising from chronic inflammation. To better characterize the progression from inflammation to cancer to metastasis, we perform…

2022
Frontiers in immunology ·doi:10.3389/fimmu.2022.923194

Ovarian cancer is the most common and lethal gynecological tumor in women worldwide. High-grade serous ovarian carcinoma (HGSOC) is one of the histological subtypes of epithelial ovarian cancer, accounting for 70%. It often occurs at later …