Heather A Harris

No ORCID on file · 4 papers in corpus · active 2004-2008

Study types

  • other 2
  • article 1
  • review 1

Condition tags

  • endometriosis 4
  • mesh:D004715 1
  • chronic_pelvic_pain 1
  • infertility 1
other 2008
Development of an early biomarker for the ovarian liability of selective estrogen receptor modulators in rats
The Journal of steroid biochemistry and molecular biology ·doi:10.1016/j.jsbmb.2008.08.008

Selective estrogen receptor modulators (SERMs) have the potential to treat estrogen sensitive diseases such as uterine leiomyoma and endometriosis, which are prevalent in reproductive age women. However, SERMs also increase the risk of deve…

review 2007
Estrogen receptor-beta: recent lessons from in vivo studies
Molecular endocrinology (Baltimore, Md.) ·doi:10.1210/me.2005-0459

The unexpected discovery of a second form of the estrogen receptor (ER), designated ERbeta, surprised and energized the field of estrogen research. In the 9 yr since its identification, the remarkable efforts from academic and industrial sc…

other 2006
An estrogen receptor-beta agonist is active in models of inflammatory and chemical-induced pain
European journal of pharmacology ·doi:10.1016/j.ejphar.2006.09.033

ERB-041 (2-(3-Fluoro-4-hydroxyphenyl)-7-vinyl-1,3 benzoxazol-5-ol) is a selective estrogen receptor-beta agonist with activity in rodent models of rheumatoid arthritis and endometriosis. Clinical trials for these diseases are underway: howe…

article 2004
A selective estrogen receptor-β agonist causes lesion regression in an experimentally induced model of endometriosis
Human Reproduction ·doi:10.1093/humrep/deh711

BACKGROUND: Endometriosis is a common gynaecological problem of uncertain aetiology. It affects primarily young, reproductive-aged women and can result in chronic pelvic pain and infertility. Current approved therapies have significant side…