Jian Cao

ORCID: 0000-0001-9395-0387 · 9 papers in corpus
lab-animal 2025
Reproductive sciences (Thousand Oaks, Calif.) ·doi:10.1007/s43032-025-01944-1

Adenomyosis (AM), a gynecological disorder that severely affects female reproductive health. AM-associated macrophage (AAM) polarization-induced epithelial-mesenchymal transition (EMT) is a key driver of AM progression. In this study, we in…

diagnostic-accuracy 2025
·doi:10.21203/rs.3.rs-6696073/v1

Abstract Delayed diagnosis of endometriosis (EM) can significantly hinder treatment options and patient prognosis, adversely affecting fertility and increasing the risk of malignancy. Current diagnostic methods are invasive. In our study, …

diagnostic-accuracy 2025
Gene ·doi:10.1016/j.gene.2025.149777

Adenomyosis (AM) is a common non-cancerous condition of the uterus that has significant effects on women's health. Despite its clinical importance, the advancement of dependable non-invasive diagnostic biomarkers has yet to be achieved. Thi…

review 2024
American journal of reproductive immunology (New York, N.Y. : 1989) ·doi:10.1111/aji.13841

Adenomyosis (AM) is a common gynecological disorder characterized by the presence of endometrial glands and stroma within the uterine myometrium. It is associated with abnormal uterine bleeding (AUB), dysmenorrhea, and infertility. Although…

lab-animal 2024
Archives of gynecology and obstetrics ·doi:10.1007/s00404-024-07854-y

PURPOSE: This study aimed to establish a protocol for efficiently isolating and expanding adenomyotic lesion-derived endometrial mesenchymal stem cells (A-eMSCs) in vitro. METHODS: Three different methods-namely, the enzymatic method, the …

2022
·doi:10.6084/m9.figshare.19808496

This study aimed to identify differentially expressed genes (DEGs) and molecular pathways in eutopic endometrial stromal cells (EuESCs) from adenomyosis (AM) patients and to provide a new insight into the disease mechanisms. The gene expres…

other 2022
Bioengineered ·doi:10.1080/21655979.2022.2077614

This study aimed to identify differentially expressed genes (DEGs) and molecular pathways in eutopic endometrial stromal cells (EuESCs) from adenomyosis (AM) patients and to provide a new insight into the disease mechanisms. The gene expres…

lab-animal 2019
The journal of physiological sciences : JPS ·doi:10.1007/s12576-018-0634-4

Mitochondrial homeostasis is closely associated with liver cancer progression via multiple mechanisms and is also a potential tumour-suppressive target in clinical practice. However, the role of mitochondrial fission in liver cancer cell vi…

lab-animal 2018
Cell stress & chaperones ·doi:10.1007/s12192-018-0937-7

Matrine is a natural alkaloid isolated from the root and stem of the legume plant Sophora. Its anti-proliferative and pro-apoptotic effects on several types of cancer have been well-documented. However, the role of matrine in regulating mit…