Ramadan A.M. Hemeida

ORCID: 0009-0000-1870-9585 · 2 papers in corpus

article 2025

Buspirone ameliorates premature ovarian insufficiency evoked by cyclophosphamide in female rats; attention to AMPK/Nrf2/HO-1, α-Klotho/NLRP3/Caspase-1, and Caspase-3-mediated apoptosis interplay

·doi:10.1016/j.taap.2025.117373

This study aims to investigate the protective impact of buspirone (BUS) against cyclophosphamide (CPA)-induced premature ovarian insufficiency (POI) by focusing on pyroptosis, apoptosis, and the AMPK/Nrf2/HO-1 signaling pathway. POI was ach…

review 2025

Molecular mechanisms underlying cyclophosphamide-induced ovarian injury and protective strategies

·doi:10.1007/s00210-025-04550-9

Cyclophosphamide (CP) is an anti-cancer medication that also treats chronic inflammatory illnesses caused by the immune system. Although CP is widely used, it can occasionally have limited therapeutic efficacy due to its significant combine…