Yunkai Xie

No ORCID on file · 7 papers in corpus · active 2022-2025

Study types

  • article 4
  • other 1
  • preprint 1
  • review 1

Condition tags

  • endometriosis 5
  • adenomyosis 2
  • dysmenorrhea 1
  • infertility 1
article 2025
How telomere maintenance affects endometriosis development: a preliminary study
International journal of medical sciences ·doi:10.7150/ijms.102646

Background: Endometriosis results in dysmenorrhea, dyspareunia, chronic pelvic pain and infertility in reproductive-age women. However, no effective treatment methods have been applied to the disease, and the pathogenesis of endometriosis i…

article 2023
BIBR1532 Affects Endometrial Cell Proliferation, Migration, and Invasion in Endometriosis via Telomerase Inhibition and MAPK Signaling
Gynecologic and obstetric investigation ·doi:10.1159/000530460

OBJECTIVES: The effect of telomerase inhibitor BIBR1532 on endometriotic cells was investigated to explore the inhibitory effect of targeting telomerase on endometriosis. DESIGN: In vitro primary cell culture study. Participants/Materials:…

article 2023
Determination of soluble HLA-G serum levels in patients with adenomyosis and uterine fibroids before and after surgery
Human immunology ·doi:10.1016/j.humimm.2023.03.006

Adenomyosis is a benign gynaecological disease caused by the growth of endometrial tissue in the myometrium that affects approximately 30 % of child-bearing-age women. We evaluated the levels of soluble human leukocyte antigen G (sHLA-G) in…

article 2023
Metformin Inhibits the Estrogen-mediated Epithelial-Mesenchymal Transition of Ectopic Endometrial Stromal Cells in Endometriosis
In vivo (Athens, Greece) ·doi:10.21873/invivo.13356

BACKGROUND/AIM: Endometriosis is an estrogen-dependent disease characterized by the ectopic implantation and growth of endometrial tissue outside the uterus. Endometrial stromal cells (ESCs) play a crucial role in the pathogenesis of endome…

review 2023
Ovarian Clear Cell Carcinoma: Genomic Characterization, Pathogenesis and Targeted Therapy
Anticancer research ·doi:10.21873/anticanres.16515

Ovarian clear cell carcinomas (OCCCs) are a subtype of ovarian epithelial tumors that arise from the malignant transformation of endometriosis (EMs). These tumors have distinctive molecular features, high malignant potential, low sensitivit…

other 2023
Telomere-related genes as potential biomarkers to predict endometriosis and immune response: Development of a machine learning-based risk model
Frontiers in medicine ·doi:10.3389/fmed.2023.1132676

INTRODUCTION: Endometriosis (EM) is an aggressive, pleomorphic, and common gynecological disease. Its clinical presentation includes abnormal menstruation, dysmenorrhea, and infertility, which seriously affect the patient's quality of life.…

preprint 2022
HLA-G is highly expressed in the serum of patients with adenomyosis
·doi:10.22541/au.164864558.81005880/v1

Objective To evaluate the expression of soluble human leukocyte antigen G(sHLA-G) in serum of patients with adenomyosis.Methods 34 patients with adenomyosis and 31 patients with uterine fibroids diagnosed histologically were selected as sub…