Wollborn L

No ORCID on file · 3 papers in corpus · active 2024-2026
2026
A lasso-based model combining miRNA and clinical variables predicts future risk of breast and ovarian cancer.
Scientific reports ·doi:10.1038/s41598-026-45020-3

Hereditary breast and ovarian cancer syndrome (HBOC) is principally caused by germline mutations in BRCA1 and BRCA2. However, most women with HBOC are undiagnosed, and some patients meeting clinical criteria for HBOC will have no identifiab…

2025
Effects of Clinical Covariates on Serum miRNA Expression among Women without Ovarian Cancer.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology ·doi:10.1158/1055-9965.epi-23-1355

BackgroundSerum miRNAs are potential biomarkers for ovarian cancer; however, many factors may influence miRNA expression. To understand potential confounders in miRNA analysis, we examined how sociodemographic factors and comorbidities, inc…

2024
Serum miRNA improves the accuracy of a multivariate index assay for triage of an adnexal mass.
Gynecologic Oncology ·doi:10.1016/j.ygyno.2024.08.008

ObjectiveTo determine whether a multimodal assay combining serum microRNA with protein biomarkers and metadata improves triage assessment of an adnexal mass.MethodsSerum samples from 468 training subjects (191 cancer cases and 277 benign ad…