Abstract Uterine leiomyomata (UL) are the most common neoplasms of the female reproductive tract and primary cause for hysterectomy, leading to considerable morbidity and high economic burden. Here we conduct a GWAS meta-analysis in 35,474 …
Discovery of novel loci for endometriosis in genome-wide association analysis of 63K cases and 700K controls Study question (maximum 25 words):What common genetic variants and corresponding functional mechanisms, underlie endometriosis, and…
Endometriosis is a common complex condition with an estimated heritability of 50%. The largest meta-analysis of genome-wide association studies (GWAS) for endometriosis to date, including 17K cases, identified 14 genome-wide significant loc…
Epidemiological studies have demonstrated associations between endometriosis and certain histotypes of ovarian cancer, including clear cell, low-grade serous and endometrioid carcinomas. We aimed to determine whether the observed associatio…