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- D'Souza SS 2
- Murty SB 2
- Qiu W 2
- Thanoo BC 2
- Kostanski JW 1
- Al-Ghananeem A 1
- Schrier B 1
- Selmin F 1
- Sohn M 1
- Mansour HM 1
Controlled release delivery is available for many routes of administration and offers many advantages (as microparticles and nanoparticles) over immediate release delivery. These advantages include reduced dosing frequency, better therapeut…
The purpose of this study was to determine the feasibility of applying accelerated in vitro release testing to correlate or predict long-term in vitro release of leuprolide poly(lactide-co-glycolide) microspheres. Peptide release was studie…
The purpose of this study was to assess whether male rats whose testosterone levels were suppressed to castration levels (<0.5 ng/mL) for a 1-year period by the sustained delivery of orntide acetate, a GnRH antagonist, would return to ferti…
BackgroundAntagonistic analogues of GnRH for the treatment of prostate cancer may be used clinically in persons for whom return to fertility after such treatment is important or desirable. The purpose of this study was, therefore, to evalua…