Yingfang Zhou

OBJECTIVE: To investigate the effects of angiogenesis inhibitor TNP-470 on uterine microvessels in mice. Pituitary grafting frequently induced uterine adenomyosis. DESIGN: In vivo experimental study. SETTING: Department of Biological Scie…

OBJECTIVE: To investigate the role of angiogenesis and expression of vascular endothelial growth factor (VEGF) in the pathophysiology of adenomyosis of the uterus. METHODS: The study included 32 patients with histologically proven adenomyo…

Objective To investigate the incidence, clinical characteristics, diagnosis and treatment of uterine ade-nomyosis.Methods Clinical data of 318 patients with adenomyosis confirmed by pathology from January 1997 to December 1999 admitted in o…

The inhibitory effects of a novel, orally active matrix metalloproteinase (MMP) inhibitor, ONO-4817, on the development of uterine adenomyosis induced experimentally by pituitary grafting were examined in mice. Mice were given transplants o…

Objective Thirty mature female ICR mice were used in order to develop an animal model of subcutaneous endometriosis. Methods Experimental endometriosis was produced by autotiansplantation of uterine fragments to subcutaneous region of the a…

Changes in uterine blood vessels were evaluated quantitatively by an immunohistochemical study using an antibody to von Willebrand factor (vWF) during the development of experimentally induced adenomyosis in mice. In all mice treated with p…

OBJECTIVE: To investigate the value of serum CA125 assays in the diagnosis of uterine adenomyosis. METHODS: Fifty-five consecutive patients with uterine-adenomyosis and twenty with leiomyoma of uterus, diagnosed by surgery and pathology we…

In order to study the risk factors associated with pelvic endometriosis, a case-control study was carried out from Mar. 1991 to Feb. 1993 in our gynecological ward. A total of 190 cases with endometriosis and 192 patients with non-endometri…