Konecny GE

No ORCID on file · 3 papers in corpus · active 2013-2025
2025
Early Detection of Ovarian Cancer Using Cell-Free DNA Fragmentomes and Protein Biomarkers.
Cancer discovery ·doi:10.1158/2159-8290.cd-24-0393

SignificanceThere is an unmet need for effective ovarian cancer screening and diagnostic approaches that enable earlier-stage cancer detection and increased overall survival. We have developed a high-performing accessible approach that eval…

2016
Molecular classification of high grade endometrioid and clear cell ovarian cancer using TCGA gene expression signatures.
Gynecologic Oncology ·doi:10.1016/j.ygyno.2016.02.023

BackgroundIt is unclear whether the transcriptional subtypes of high grade serous ovarian cancer (HGSOC) apply to high grade clear cell (HGCCOC) or high grade endometrioid ovarian cancer (HGEOC). We aim to delineate transcriptional profiles…

2013
Epigenetic analysis leads to identification of HNF1B as a subtype-specific susceptibility gene for ovarian cancer.
Nature communications ·doi:10.1038/ncomms2629

HNF1B is overexpressed in clear cell epithelial ovarian cancer, and we observed epigenetic silencing in serous epithelial ovarian cancer, leading us to hypothesize that variation in this gene differentially associates with epithelial ovaria…