Zhang C

Endometriosis (EMs) is a gynecological disorder characterized by chronic inflammation and an aberrant immune microenvironment. In this study, we integrated the GSE6364 dataset from the GEO database to identify differentially expressed genes…

The objective was to assess outcomes of robotic-assisted transvaginal natural orifice transluminal endoscopic surgery (RA-vNOTES) performed for hysterectomy and endometriosis excision. We conducted a retrospective case series across two hos…

Chronic pancreatitis (CP) is characterized by irreversible fibrotic destruction and impaired pancreatic function. CP disrupts lipid metabolism and causes the imbalance of gut microbiota which in turn exacerbates pancreatic fibrosis. Statins…

The present study aimed to explore whether there is an association between the transfer of frozen thawed embryos (FET) obtained during SARS-CoV-2 infection and an increased risk of adverse pregnancy outcomes. We performed a case-control coh…

Objectives: To explore the feasibility and surgical outcomes of robot-assisted vaginal natural orifice transluminal endoscopic surgery (RA-vNOTES) for women suffering from gynecologic disease. Methods: We performed an observational study re…

BackgroundTuberculosis can negatively impact both overall health and female reproductive function. This study investigated the relationship between the interferon-gamma release assay (IGRA) status and pregnancy outcomes in infertile women, …

OBJECTIVE: Infertility caused by endometriosis (EM) directly affects the possibility of pregnancy in women of gestational age. This study aims to establish a prediction model to accurately predict the natural pregnancy outcome of patients w…

Qiumin He,1,* Chongyuan Zhang,2,* Yao Hu,1 Jinfang Deng,1 Shuirong Zhang1 1Department of Gynaecology,Jingzhou Central Hospital, Jingzhou Hospital Affiliated to Yangtze University, Jingzhou, Hubei, 434020, People’s Republic of China; 2Depart…

This study aimed to investigate the association between insulin resistance (IR) and recurrent pregnancy loss (RPL) in patients undergoing assisted reproductive technology (ART). A retrospective analysis compared glucose and insulin indices …

OBJECTIVE: To summarize evidence on the efficacy and safety of the levonorgestrel-releasing intrauterine system (LNG-IUS) in managing adenomyosis (AM), both as a monotherapy and in combination with other therapies. METHODS: We searched Med…

The endometrial receptive status is critical for a successful embryo implantation, but it only last for a short period of time, and the window of implantation (WOI) of each woman changes individually, which will lead to poor outcomes of ass…

BACKGROUND: Infertility poses a significant burden on both global and national scales. However, the epidemiology of primary infertility among reproductive-aged couples in China remains poorly understood. Therefore, this study aimed to inves…

In the face of declining global birth rates, women's health status remains a critical yet often overlooked determinant. This review summarises evidence on how various aspects of women's health, including nutrition and lifestyle, socioeconom…

The aim of the case control study was to compare surgical outcomes of transvaginal natural orifice transluminal endoscopic surgery (vNOTES) hysterectomy with the da Vinci surgical system (dVSS) and conventional vNOTES. A case control study …

Alarmins are a class of molecules released when affected cells damaged or undergo apoptosis. They contain various chemotactic and immunomodulatory proteins or peptides. These molecules regulate the immune response by interacting with patter…

BACKGROUND: Amphiregulin (AR) is a growth factor that resembles the epidermal growth factor (EGF) and serves various functions in different cells. However, no systematic studies or reports on the role of AR in human oocytes have currently b…

BACKGROUND: With the increasing incidence of obesity and the childbearing-age delay among women, a debate over obesity's impacts on pregnancy and neonatal outcomes becomes hot. The potential negative effects of obesity and aging on fertilit…

Background: Endometriosis is a debilitating and highly stigmatized chronic condition. The relationship between stigma and depressive symptoms among college-attending women with endometriosis symptoms was examined. Method: Data were analyzed…

RESEARCH QUESTION: Are there correlations between the biological expression of steroid receptors and the extent of fibrosis in adenomyotic lesions, and the treatment effectiveness of the levonorgestrel-releasing intrauterine system (LNG-IUS…

Biofilm-related infections (BRIs) present significant challenges owing to drug resistance, adverse immune responses, and implant failure; however, current approaches inadequately cater to the diverse therapeutic requirements at different st…

Endometriosis (EM) is a common gynecologic condition that often leads to infertility in women of reproductive age. Cell adhesion molecule 2 (CADM2) is involved in maintaining cell adhesion and polarity, as well as suppressing tumors. Howeve…

INTRODUCTION: Invasive Stratified Mucin-producing Carcinoma (ISMC) of the cervix is a newly named cervical adenocarcinoma associated with Human Papilloma virus (HPV). Due to its relative rarity, clinical data, pathological features, and mol…

PURPOSE: To investigate potential differences in pregnancy outcomes among patients with regular menstruation who underwent frozen-thawed embryo transfer using natural cycle (NC) or hormone replacement therapy (HRT). METHODS: This study ret…

INTRODUCTION: Endometriosis, a common and distressing gynecological condition, affects fertility and causes pain, is often managed with medications such as Elagolix. The present study aimed to construct a physiologically based pharmacokinet…