Sefa Arlier

No ORCID on file · 4 papers in corpus
review 2017
Endoplasmic Reticulum Stress and Homeostasis in Reproductive Physiology and Pathology
International journal of molecular sciences ·doi:10.3390/ijms18040792

The endoplasmic reticulum (ER), comprises 60% of the total cell membrane and interacts directly or indirectly with several cell organelles i.e., Golgi bodies, mitochondria and proteasomes. The ER is usually associated with large numbers of …

lab-animal 2017
p38 Mitogen-Activated Protein Kinase is Involved in the Pathogenesis of Endometriosis by Modulating Inflammation, but not Cell Survival
Reproductive sciences (Thousand Oaks, Calif.) ·doi:10.1177/1933719117725828

BACKGROUND: Local pro-inflammatory environment and enhanced cell survival contribute to the endometriosis development. A serine/threonine kinase p38 mitogen-activated protein kinase (MAPK) mediates intracellular signaling of cytokine produc…

lab-animal 2017
The extracellular signal-regulated kinase 1/2 triggers angiogenesis in human ectopic endometrial implants by inducing angioblast differentiation and proliferation
American journal of reproductive immunology (New York, N.Y. : 1989) ·doi:10.1111/aji.12760

PROBLEM: The role of extracellular signal-regulated kinase (ERK)1/2-mediated angiogenesis during endometriotic nidation is unknown. We posit that ERK1/2-induced angioblast differentiation and proliferation promotes ectopic endometrial angio…

review 2016
The role of decidual cells in uterine hemostasis, menstruation, inflammation, adverse pregnancy outcomes and abnormal uterine bleeding
Human Reproduction Update ·doi:10.1093/humupd/dmw004

BACKGROUND: Human pregnancy requires robust hemostasis to prevent hemorrhage during extravillous trophoblast (EVT) invasion of the decidualized endometrium, modification of spiral arteries and post-partum processes. However, decidual hemorr…