Thomas D'Hooghe

No ORCID on file · 134 papers in corpus · active 1996-2026

Study types

  • article 67
  • review 29
  • other 28
  • editorial 2
  • book-chapter 2

Condition tags

  • endometriosis 106
  • mesh:D004715 83
  • infertility 27
  • dysmenorrhea 5
  • mesh:D017699 3
  • die_deep_infiltrating 3
  • adenomyosis 3
  • mesh:D004412 2
  • chronic_pelvic_pain 1
  • mesh:D004716 1
other 2026
Fertility and sterility ·doi:10.1016/j.fertnstert.2026.03.020

OBJECTIVE: To examine intrapatient variability in retrieved oocyte numbers across consecutive in vitro fertilization (IVF) ovarian stimulation (OS) cycles with an identical OS protocol. DESIGN: Cross-continental, multicenter retrospective …

other 2026
Fertility and sterility ·doi:10.1016/j.fertnstert.2025.12.010
other 2025
Gynecologic and obstetric investigation ·doi:10.1159/000542074

OBJECTIVE: Various gonadotropins are used for ovarian stimulation (OS). This study investigated the cost-effectiveness of different gonadotropins based on real-world data from the French National Health Database (SNDS) over a 7-year follow-…

review 2025
Fertility and sterility ·doi:10.1016/j.fertnstert.2025.06.026

OBJECTIVE: To address the reporting of minimal clinically important differences (MCIDs) in the published literature and investigate the utility of absolute and relative differences when defining this parameter. DESIGN: Expert opinion. SUB…

other 2025
Fertility and sterility ·doi:10.1016/j.fertnstert.2024.10.001

OBJECTIVE: To assess the adequate ovarian follicular development and oocyte recovery between ovarian potential (antral follicle count [AFC]) before the start of ovarian stimulation (OS) and oocyte quantity and quality at oocyte retrieval. A…

other 2025
Fertility and sterility ·doi:10.1016/j.fertnstert.2025.05.168

OBJECTIVE: To provide a framework for conducting rigorous nonrandomized studies of interventions in fertility treatment research, addressing their role as complements to randomized controlled trials (RCTs) in evaluating treatment outcomes. …

other 2024
International journal of molecular sciences ·doi:10.3390/ijms25179405

Highly purified human menopausal gonadotropin (HP-hMG [Menopur®, Ferring Pharmaceuticals, Saint-Prex, Switzerland]) contains a 1:1 ratio of follicle-stimulating hormone (FSH) and luteinizing hormone (LH). This analysis aimed to assess gonad…

article 2024
Biomedicines ·doi:10.3390/biomedicines12040888

The aim of this systematic review is to assess the power of circulating miRNAs as biomarkers as a diagnostic tool in endometriosis. In endometriosis-suspected women with uncertain imaging, the only way to confirm or exclude endometriosis wi…

other 2024
Expert opinion on drug delivery ·doi:10.1080/17425247.2024.2311127

BACKGROUND: This study aimed to confirm that the incremental dose/clicks system dispenses accurate doses for the Merck family of fertility pen injectors. RESEARCH DESIGN AND METHODS: Set doses (Vset) for three dose dial settings (minimum d…

other 2024
Reproductive biomedicine online ·doi:10.1016/j.rbmo.2023.103725

RESEARCH QUESTION: According to real-world data, is recombinant human FSH (r-hFSH) combined with recombinant human LH (r-hLH) or r-hFSH alone more effective for women of advanced maternal age (AMA) in terms of live birth? DESIGN: Non-inter…

preprint 2024
·doi:10.1101/2024.03.28.583957

ABSTRACT Background Endometriosis is a complex disease, and its pathophysiology is still unclear. Therefore, endometriosis animal models need to be carefully selected and examined to be useful for identification of novel therapies for women…

other 2024
Reproductive biology and endocrinology : RB&E ·doi:10.1186/s12958-024-01291-x

BACKGROUND: Currently, there is no consensus on the optimal management of women with low prognosis in ART. In this Delphi consensus, a panel of international experts provided real-world clinical perspectives on a series of literature-suppor…

other 2023
International journal of molecular sciences ·doi:10.3390/ijms24098040

Various preparations of follicle-stimulating hormone (FSH) are commercially available; however, they differ in glycoforms composition and purity owing to their respective sources. Additional chemical/physical changes can also be introduced …

other 2023
Best practice & research. Clinical obstetrics & gynaecology ·doi:10.1016/j.bpobgyn.2022.102308

This comparative non-interventional study using data from the French National Health Database (Système National des Données de Santé) investigated real-world (cumulative) live birth outcomes following ovarian stimulation, leading to oocyte …

review 2023
International journal of molecular sciences ·doi:10.3390/ijms24109020

Follicle-stimulating hormone (FSH), together with luteinizing hormone (LH) and human chorionic gonadotropin (hCG), plays a fundamental role in human reproduction. The discovery of FSH and other gonadotropins was a defining moment in our und…

other 2023
Journal of gynecology obstetrics and human reproduction ·doi:10.1016/j.jogoh.2023.102640
meta-analysis 2023
Nature genetics ·doi:10.1038/s41588-023-01323-z

Endometriosis is a common condition associated with debilitating pelvic pain and infertility. A genome-wide association study meta-analysis, including 60,674 cases and 701,926 controls of European and East Asian descent, identified 42 genom…

other 2023
Gynecologic and obstetric investigation ·doi:10.1159/000529304

OBJECTIVES: The objective of this study was to examine the prevalence of chronic endometritis (CE) in infertile women, its impact on reproductive outcomes, and the accuracy of hysteroscopy as a screening tool for CE. DESIGN: This was a pro…

other 2023
Best practice & research. Clinical obstetrics & gynaecology ·doi:10.1016/j.bpobgyn.2023.102340

Willingness to pay (WTP) for an infertility treatment is the maximum amount of money a patient is willing to pay per treatment, or to achieve a live birth or pregnancy. Such thresholds are important to determine the cost effectiveness of a …

review 2023
Best practice & research. Clinical obstetrics & gynaecology ·doi:10.1016/j.bpobgyn.2022.102301

A high ovarian response to conventional ovarian stimulation (OS) is characterized by an increased number of follicles and/or oocytes compared with a normal response (10-15 oocytes retrieved). According to current definitions, a high respons…

other 2022
International journal of molecular sciences ·doi:10.3390/ijms23126762

Although the full primary structures of the alfa and beta subunits of reference r-hFSH-alfa and its biosimilars are identical, cell context-dependent differences in the expressing cell lines and manufacturing process can lead to variations …

article 2022
·doi:10.60692/myypc-em434

A Delphi consensus was conducted to evaluate the influence of single nucleotide polymorphisms (SNPs) in genes encoding gonadotropin and gonadotropin receptors on clinical ovarian stimulation outcomes following assisted reproductive technolo…

article 2022
·doi:10.60692/j2kq0-1jw63

A Delphi consensus was conducted to evaluate the influence of single nucleotide polymorphisms (SNPs) in genes encoding gonadotropin and gonadotropin receptors on clinical ovarian stimulation outcomes following assisted reproductive technolo…

review 2021
Human Reproduction ·doi:10.1093/humrep/deab254

STUDY QUESTION: Is there a shared genetic or causal association of endometriosis with asthma or what biological mechanisms may underlie their potential relationships? SUMMARY ANSWER: Our results confirm a significant but non-causal associat…

article 2021
·doi:10.1093/humrep/deab130.329

Abstract Study question Is endometriosis related to worse outcome of assisted reproductive techniques (ART)? Summary answer Cumulative incidence of live birth in patients with and without endometriosis at laparoscopy was similar, although d…