Wittmann BM

No ORCID on file · 3 papers in corpus · active 2010-2017
2017
A driver role for GABA metabolism in controlling stem and proliferative cell state through GHB production in glioma.
Acta neuropathologica ·doi:10.1007/s00401-016-1659-5

Cell populations with differing proliferative, stem-like and tumorigenic states co-exist in most tumors and especially malignant gliomas. Whether metabolic variations can drive this heterogeneity by controlling dynamic changes in cell state…

2010
Mechanisms of progesterone receptor inhibition of inflammatory responses in cellular models of breast cancer.
Molecular endocrinology (Baltimore, Md.) ·doi:10.1210/me.2010-0289

Both pro- and antimitogenic activities have been ascribed to progesterone receptor (PR) agonists and antagonists in breast cancer cells; however, the transcriptional responses that underlie these paradoxical functions are not apparent. Usin…

2010
Regulation of aryl hydrocarbon receptor function by selective estrogen receptor modulators.
Molecular endocrinology (Baltimore, Md.) ·doi:10.1210/me.2009-0339

Selective estrogen receptor modulators (SERMs), such as tamoxifen (TAM), have been used extensively for the treatment and prevention of breast cancer and other pathologies associated with aberrant estrogen receptor (ER) signaling. These com…