Juan Gu

ORCID: 0000-0002-9434-5776 · 4 papers in corpus
article 2026
USP2 is associated with mitochondrial respiratory activity and cell viability in endometrial stromal cells in endometriosis
·doi:10.1186/s12905-026-04781-9

Mitochondrial dysfunction has been implicated in the pathophysiology of endometriosis, but the role of ubiquitin-specific protease 2 (USP2) remains unclear. This study aimed to determine whether USP2 modulates mitochondrial respiratory acti…

other 2025
Single-cell and spatially resolved omics reveal transcriptional and metabolic signatures of ovarian endometriomas
Nature communications ·doi:10.1038/s41467-025-66706-8

Endometriosis involves ectopic growth of endometrial-like tissue, yet the spatial transcriptomic and metabolic landscape of ovarian endometriomas remains poorly understood. This investigation presents a comprehensive multi-omics analysis of…

article 2025
Single-cell transcriptome unveils mesenchymal cell diversity in endometriosis
Human molecular genetics ·doi:10.1093/hmg/ddaf065

Mesenchymal cells constitute the primary structural support elements within endometriotic lesions, yet their pivotal roles in endometriotic pathogenesis remain largely uncharted. This study aimed to construct a single-cell atlas of endometr…

other 2025
The application of progesterone-primed ovarian stimulation protocol in patients with ovarian endometriosis combined with diminished ovarian reserve
BMC women's health ·doi:10.1186/s12905-025-03601-w

PURPOSE: The aim was to investigate the value of the application of a progesterone-primed ovarian stimulation (PPOS) protocol in patients with ovarian endometriosis (OEM) combined with diminished ovarian reserve (DOR). MATERIALS AND METHOD…