Zilu Wang

No ORCID on file · 9 papers in corpus · active 2021-2026

Study types

  • article 3
  • review 3
  • other 2
  • preprint 1

Condition tags

  • adenomyosis 6
  • mesh:D004715 3
  • endometriosis 3
  • infertility 1
  • mesh:D004716 1
review 2026
Mechanistic insights into inflammatory cytokines in adenomyosis‑induced infertility (Review)
International journal of molecular medicine ·doi:10.3892/ijmm.2026.5778

Adenomyosis (AM), an estrogen‑dependent chronic inflammatory disease with a rising incidence, has emerged as a major cause of infertility and reduced clinical pregnancy rates in reproductive‑aged women, severely impairing reproductive healt…

article 2026
Molecular mechanism of active ingredients from Ramulus Cinnamomi<italic>-</italic>Rhizoma Paridis regulating PI3K/AKT and HIF-1α pathway to inhibit the progression of uterine adenomyosis
·doi:10.70976/j.1008-0805.szgygy-2026-0205

目的 探讨桂枝-重楼有效成分联用抑制子宫腺肌病（AM）进展的相关分子机制。 方法 利用梯度浓度的重楼皂苷（PP）I、II、VII（PPI、PPII、PPVII）及桂枝有效成分反式肉桂醛（TCA）分别处理子宫腺肌病原代细胞（AMDC），通过CCK-8法检测药物对AMDC活力的影响；正交实验筛选PPII与TCA最佳配比（简称PT），Transwell检测细胞侵袭、迁移能力；网络药理学筛选出PT治疗AM的关键通路；利用梯度浓度的PT腹腔注射ICR小鼠30 d，评价药物的安全性…

review 2025
Extracellular vesicles in endometrial-related diseases: role, potential and challenges
PeerJ ·doi:10.7717/peerj.19041

Endometrial dysfunction underlies many common gynecologic disorders, such as endometriosis, endometrial cancer, intrauterine adhesions, and endometritis, which affect many women around the world. Extracellular vesicles play an important rol…

other 2025
Identification of metabolic reprogramming-associated biomarkers in endometriosis through integrated bioinformatics analysis
Hereditas ·doi:10.1186/s41065-025-00590-6

BACKGROUND: Endometriosis (EMs), a common gynecological disorder, involves complex molecular mechanisms. Metabolic reprogramming (MR) has been recognized as a hallmark of EMs, contributing to lesion survival and immune microenvironment remo…

article 2025
Tongmai Huazheng mixture attenuates adenomyosis by inducing ferroptosis through suppression of the JAK2/STAT3 signaling pathway
Phytomedicine : international journal of phytotherapy and phytopharmacology ·doi:10.1016/j.phymed.2025.157748
article 2023
Establishment of an immortalized cell line derived from human adenomyosis ectopic lesions
Tissue & cell ·doi:10.1016/j.tice.2023.102284

Because adenomyosis (AM) ectopic primary cells are hard to come by, have a short lifespan, and the characteristics that alter over time, their utility in AM research is constrained. This study aimed to establish a line of immortalized human…

other 2022
Analysis of the Mechanism of GuizhiFuling Wan in Treating Adenomyosis Based on Network Pharmacology Combined with Molecular Docking and Experimental Verification
Evidence-based complementary and alternative medicine : eCAM ·doi:10.1155/2022/6350257

BACKGROUND: The effect of GuizhiFuling Wan (GFW) on adenomyosis (AM) is definite. This study aimed to explore the mechanism and key therapeutic targets of GFW in treating AM through network pharmacology combined with molecular docking and e…

preprint 2022
Trans-Cinnamaldehyde inhibition of cytoskeleton-induced invasion and migration by regulating the Rho/ROCK pathway in adenomyosis
·doi:10.22541/au.165519364.49734412/v1

Some of the key steps in adenomyosis (AM) are the migration and invasion of adenomyosis derived cells (AMDC); these processes require rearrangement of the cytoskeleton which Rho/ROCK signaling pathway is involved. The aim of the current stu…

review 2021
Traditional Chinese medicine prescription Guizhi Fuling Pills in the treatment of endometriosis
International journal of medical sciences ·doi:10.7150/ijms.55789

Endometriosis (EMs) is recorded as Zheng Jia in traditional Chinese medicine (TCM) books. Guizhi Fuling Pills (GFPs), a classic prescription for promoting blood circulation and removing blood stasis, is widely used for women's blood stasis …