Giordano G

No ORCID on file · 5 papers in corpus · active 2015-2024

Study types

  • article 1

Condition tags

  • adenomyosis 1
2024
AI Based Discovery of a New AKR1C3 Inhibitor for Anticancer Applications.
ACS medicinal chemistry letters ·doi:10.1021/acsmedchemlett.4c00150

AKR1C3 is an upregulated enzyme in prostate and other cancers; in addition to regulating hormone synthesis, this enzyme is thought to play a role in the aggressiveness of tumors and in the defense against drugs. We here used an unbiased met…

2022
Genetic regulation of iron homeostasis in sideropenic patients with mild COVID-19 disease under a new oral iron formulation: Lessons from a different perspective.
Immunobiology ·doi:10.1016/j.imbio.2022.152297

BackgroundSevere Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) needs iron to replicate itself. Coronaviruses are able to upregulate Chop/Gadd153 and Arg1 genes, consequently leading to CD8 lymphocytes decrease, degradation of aspara…

2022
How Do Drugs Affect the Skeleton? Implications for Forensic Anthropology.
Biology ·doi:10.3390/biology11040524

Forensic anthropologists rely on a number of parameters when analyzing human skeletal remains to assist in the identification of the deceased, predominantly age-at-death, sex, stature, ancestry or population affinity, and any unique identif…

2019
Morphology and Molecular Features of Rare Colorectal Carcinoma Histotypes.
Cancers ·doi:10.3390/cancers11071036

Several histopathological variants of colorectal carcinoma can be distinguished, some associated with specific molecular profiles. However, in routine practice, ninety/ninety-five percent of all large bowel tumors are diagnosed as conventio…

article 2015
Coexistence of adenomyosis and endometrioid endometrial cancer: Role in surgical guidance and prognosis estimation
Oncology letters ·doi:10.3892/ol.2015.4032

The aim of the current study was to diagnose the concomitant presence of adenomyosis (AM) in endometrioid endometrial cancer (EEC) in order to evaluate its value as an oncological prognostic marker. A retrospective analysis of 289 patients …