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Endometriosis is a common gynecological disease with high recurrence rates after surgery and the lesions keep unlimited proliferative capacity. The effect of garcinol on cell proliferation has not been investigated in endometriosis. Herein,…
BACKGROUND: The specific gut microbial signatures and their correlation with immune-inflammatory markers in infertile women with endometriosis remain underexplored.To investigate the differences in gut microbiota and their associations with…
RATIONALE: Hysterosalpingo-contrast sonography (HyCoSy) is a commonly used technique for assessing fallopian tube patency. A well-recognized complication of this procedure is venous intravasation (VI), which refers to the unintended entry o…
Intestinal endometriosis is a benign gynecological condition that frequently involves the rectosigmoid colon. Its synchronous occurrence with colorectal cancer is exceptionally rare and diagnostically challenging, particularly when mimickin…
BACKGROUND: Endometriosis is characterized by inflammation and fibrosis, in which cytokines and cytokine-macrophage interactions serve as critical mediators. However, the specific mechanisms that initiate the fibrotic cascade in endometrios…
Abstract Background Endometriosis is characterized by inflammation and fibrosis, in which cytokines and cytokine-macrophage interactions serve as critical mediators. However, the specific mechanisms that initiate the fibrotic cascade in end…
Abstract Background Endometriosis is characterized by inflammation and fibrosis, in which cytokines and cytokine-macrophage interactions serve as critical mediators. However, the specific mechanisms that initiate the fibrotic cascade in end…
Angiogenesis plays a critical role in the progression of endometriosis, with enhanced glycolysis accelerating pathological angiogenesis. Prior research has identified a central role for N6-methyladenosine (m6A) modification in regulating gl…
Introduction Uterine rupture (UR) during pregnancy refers to a disruption of the uterine wall involving the myometrium and serosa that occurs in association with pregnancy. The global incidence of UR is rising, and this condition can lead t…
BACKGROUND: This study investigates the relationship between the Dietary Inflammation Index (DII) and the risk of infertility among women of childbearing age in the United States. METHODS: This cross-sectional study analyzed data from 3184…
BACKGROUND: Matrix remodeling-associated 7 (MXRA7) plays a key role in physiological and pathological processes involving the extracellular matrix (ECM) and tissue remodeling. Recent studies have highlighted its functions in tissue injury, …
Traumatic brain injury (TBI) is a recognized global public health problem. However, there are still limitations in the available therapeutic approaches and a lack of clinically effective drugs. Therefore, an in-depth exploration of the seco…
OBJECTIVE: Building upon information quality assessment frameworks and social exchange theory, this study quantifies online doctor-patient communication quality across three dimensions using text analytics methods. Focusing on gynecological…
Metformin, the most widely used anti-diabetic drug, has been demonstrated to exert various effects, including antioxidant, anti-inflammatory, anti-tumor, and cardioprotective properties. Due to its affordability and low toxicity profile, me…
INTRODUCTION: This study investigated whether probiotics alleviate Endometriosis (EMs)-related inflammation by modulating the gut microbiota and short-chain fatty acids (SCFAs). METHODS: An endometriosis model was established in SD rats, w…
Polycystic ovary syndrome (PCOS) affects reproductive and cardiometabolic health, yet its pathogenesis remains unclear. Emerging evidence links hemoglobin levels to metabolic disorders, suggesting a potential role in PCOS development. Here,…
Endometriosis-associated ovarian carcinoma (EAOC) predominantly arises from the malignant transformation of endometriomas, yet the mechanism is incompletely defined. Spatial transcriptomic analysis of human specimens of normal endometrium, …