Jiang J

Appendiceal or cecal endometriosis with intestinal metaplasia is uncommon and may mimic mucinous tumors of the appendix. A 50-year-old woman was found incidentally to have an ileocecal lesion. In the intraoperative histological examination,…

OBJECTIVES: The aim of study was to compare the accuracy between rectal water contrast transvaginal ultrasound (RWC-TVS) and double-contrast barium enema (DCBE) in evaluating the bowel endometriosis presence as well as its extent. DESIGN AN…

BackgroundTo evaluate the short-term and long-term outcomes after laparoscopic hysterectomy (LH) compared with abdominal hysterectomy (AH) in case of benign gynecological disease.MethodsA multi-center cohort retrospective comparative study …

ObjectiveThis study aimed to assess the trend of human fecundity over time in China.MethodsThis retrospective study was conducted in Tongliao, China. Couples who were married during the time period between January 1, 1981 and December 31, 2…

Adenomyosis is a prevalent gynecologic benign disease in women. Despite its significance, there is only a limited understanding of its pathological mechanisms. Talin1, a cytoskeletal protein, plays an important role in cell survival, prolif…

OBJECTIVE: This study aims to improve the diagnostic and therapeutic efficacy through analysis of clinical and radiographic characteristics in pulmonary endometriosis. MATERIALS AND METHODS: This retrospective study was conducted from Janua…

Growth hormone (GH) is involved in the regulation of male and female infertility. Several clinical studies reveal that adjuvant GH treatment has a possible role in vitro fertilization (IVF) or intracytoplasmic sperm injection (ICSI), especi…

ObjectivesSomatic mutations in mediator complex subunit 12 (MED12) have emerged as a critical genetic change in the development of uterine leiomyomas. Studies, however, have focused largely on cohorts consisting of Caucasian patients. In th…

BACKGROUND: Endometriosis is a common cause of pain including radicular pain. Ectopic endometrial tissue may directly affect peripheral nerves including the sciatic, which has not been modelled in animals. METHODS: We developed a rat model …

AimElevated levels of sterol regulatory element-binding protein-1 (SREBP-1) have been found in endometrial cancer (EC), suggesting that it is essential to the development of EC. Obesity and diabetes have been established as known risk facto…

Modulation of a specific prostanoid synthase or receptor provides therapeutic alternatives to nonsteroidal anti-inflammatory drugs (NSAIDs) for treating pathological conditions governed by cyclooxygenase-2 (COX-2 or PTGS2). Among the COX-2 …

BackgroundRegulation of immune responses is critical for controlling inflammation and disruption of this process can lead to tissue damage. We reported that CXCL13 was induced in fallopian tube tissue following C. trachomatis infection. Her…

PURPOSE: To determine common molecular markers between endometriosis and ovarian cancer. METHODS: Patients included women who underwent laparoscopic excision of ovarian endometriotic lesions (n = 7), healthy non-pregnant women with normal …

IntroductionAn excessive inflammatory response is thought to account for the pathogenesis of sepsis and multiple organ dysfunction syndrome (MODS) after severe trauma. The interleukin-10 (IL-10) is a potent anti-inflammatory cytokine. The o…

Two anthropomorphic uterine phantoms were developed that allow assessment and comparison of strain imaging systems adapted for use with saline-infused sonohysterography (SIS). Tissue-mimicking (TM) materials consist of dispersions of safflo…

OBJECTIVE: To investigate the expressions of estrogen (E) receptor and progesterone (P) receptor in human eutopic and ectopic endometrium and the effect of mifepristone (RU486) on them. DESIGN: Prospective study. SETTING: University hospi…

OBJECTIVE: To investigate the effects of mifepristone on expression of estrogen receptor (ER) and progesterone receptor (PR) in cultured human eutopic and ectopic endometria. METHODS: Endometrial (n = 22) and endometriotic (n = 12) tissues,…

OBJECTIVE: To compare the efficacy and safety of mifepristone and danazol after conservative surgery in the treatment of patients with endometriosis. METHODS: Sixty-one patients with endometriosis (RAFS stage I-IV ) after conservative surge…

OBJECTIVE: To investigate the regulatory effects of mifepristone and progesterone on the secretion of interleukin-6 (IL-6) by endometrial and endometriosis cells in vitro. METHODS: Primary cultures of eutopic and ectopic endometrial cells f…