Piétro Santulli

Journal de Gynecologie Obstetrique et Biologie de la Reproduction - Vol. 42 - N° 4 - p. 325-333

BACKGROUND: Uterine leiomyomas (fibroids) are the most common gynaecological benign tumors in premenopausal women. Evidences support the role of oxidative stress in the development of uterine leiomyoma. We have analysed oxidative stress mar…

L endométriose est une pathologie chronique, bénigne, caractérisée par la présence de tissu endométrial (glande et stroma) en dehors de l utérus. La forte prévalence de cette maladie, sa symptomatologie invalidante et son coût annuel consid…

Endometriosis is considered as a tumor-like lesion under the World Health Organization (WHO) classification of ovarian tumors. Data from large cohort and case-control studies indicate that patients with a history of endometriosis have an in…

Adenomyosis is defined as a benign invasion of the endometrium into the myometrium. Magnetic Resonance Imaging enables the diagnosis, by measuring the thickness of a distinct low-intensity myometrial band on T2- weighted images, called Junc…

MRI and ultrasound complement each other very well for the screening and diagnosis of endometriosis. Real Time Virtual Sonography (RVS) is a new technique which uses magnetic navigation and a computer software to allow for the synchronized …

Endometrioma is a common ovarian cyst associated with pain and infertility, but its pathogenesis remains enigmatic. Demonstration of the subtelomeric location of hypermethylation in endometrioma has been reported by genome-wide profiling of…

Cytokines, and specifically interleukin 6 (IL-6) and interleukin 8 (IL-8), have been associated with the pathogenesis of endometriosis. We studied serum concentrations of IL-6 and IL-8 in patients with deep infiltrating endometriosis (DIE) …

BACKGROUND: The objective of this study was to evaluate the significance of severe preoperative pain for patients presenting with ovarian endometrioma (OMA). METHODS: Three hundred consecutive patients with histologically proven OMA were en…

Recurrence of deep endometriosis remains a major issue in the management of endometriosis. The main cause for recurrence appears to be an incomplete excisional surgery. Therefore, the goal of the primary surgery should be the complete resec…

BACKGROUND: Interleukin 33 (IL-33) is a cytokine involved in fibrotic disorders. We have analyzed IL-33 levels in the sera and peritoneal fluids of women with various forms of endometriosis and investigated the correlation with disease acti…

ObjectiveTo investigate key genes expression of the sphingosine-1-phosphate pathway in endometriotic tissues.DesignA case-control laboratory study.SettingTertiary care university hospital.Patient(s)A total of 31 women, with (n = 16) and wit…

BACKGROUND: An inverse association between BMI and endometriosis has been reported but remains controversial. We decided to evaluate the association between BMI and the different types of endometriosis, classified as superficial endometrios…